Results 81 to 90 of about 11,957,490 (337)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Efficiency of Space Heating Systems under the Climate Change [PDF]

open access: yesE3S Web of Conferences, 2019
Impacts of the climate change on the space heating systems are discussed. We have used the latest global temperature data of the Global Climate Historical Network to demonstrate that the heating and cooling demand combined is decreasing in the world ...
Klimenko Vladimir   +2 more
doaj   +1 more source

Modeling the Development of Regional Economy and an Innovation Space Efficiency

open access: yes, 2016
Forming the regional space of innovation is accompanied by the simultaneous development of various structures. The contemporary model of innovative development assumes interactions between government, industry, and universities. In this paper, the set of
V. Makarov   +4 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Analysing Compression Techniques for In-Memory Collaborative Filtering [PDF]

open access: yes, 2015
Following the recent trend of in-memory data processing, it is a usual practice to maintain collaborative filtering data in the main memory when generating recommendations in academic and industrial recommender systems.
Macdonald, Craig   +2 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Porous SiC/melamine-derived carbon foam frameworks with excellent electromagnetic wave absorbing capacity

open access: yesJournal of Advanced Ceramics, 2019
Porous three-dimensional SiC/melamine-derived carbon foam (3D-SiC/MDCF) composite with an original open pore structure was fabricated by the heat treatment of the commercial melamine foam (MF), carbonization of the stable MF, and chemical vapor ...
Xinli Ye   +8 more
doaj   +1 more source

Power efficient dynamic resource scheduling algorithms for LTE [PDF]

open access: yes, 2010
This paper presents a link level analysis of the rate and energy efficiency performance of the LTE downlink considering the unitary codebook based precoding scheme.
Armour, SMD   +4 more
core   +3 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving public hospital efficiency and fiscal space implications: the case of Mauritius

open access: yesInternational Journal for Equity in Health, 2020
Background General Government Health Expenditure (GGHE) in Mauritius accounted for only 10% of General Government Expenditure for the fiscal year 2018.
Ajoy Nundoochan
semanticscholar   +1 more source

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