Results 91 to 100 of about 1,316,261 (298)
Design Space Exploration in Cyber-Physical Systems [PDF]
, 2019 Cyber physical systems (CPS) integrate a variety of engineering areas such as control, mechanical and computer engineering in a holistic design effort.
Amir, Maral
core
Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
Optimization of patch antennas via multithreaded simulated annealing based design exploration [PDF]
, 2017 In this paper, we present a new software framework for the optimization of the design of microstrip patch antennas. The proposed simulation and optimization framework implements a simulated annealing algorithm to perform design space exploration in order
Richie, James, Ababei, Cristinel
core +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Exploring Space with FieldVenturer
, 2017 FieldVenturer is a project experimenting with a long-range remote-controlled and collaboratively-piloted vehicle. It centres on the design, development and public deployment of a Rover: a small tracked vehicle equipped with sensors and a camera and an elaborate ‘Command Centre’ through which it can be controlled by members of the public.
RTD Conference +2 more
openaire +2 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Cross-Domain Fault Diagnosis Using Knowledge Transfer Strategy: A Review
IEEE Access, 2019 Data-driven fault diagnosis has been a hot topic in recent years with the development of machine learning techniques. However, the prerequisite that the training data and the test data should follow an identical distribution prevents the conventional ...
Huailiang Zheng +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
The idea of space exploration [PDF]
Public reactions to the space program, especially to the 1969 Moon landing are discussed. Space exploration is compared to explorations during the Age of Discovery.
Mazlish, B.
core +1 more source