Results 91 to 100 of about 1,638,848 (302)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Trade studies for nuclear space power systems [PDF]
As human visions of space applications expand and as we probe further out into the universe, our needs for power will also expand, and missions will evolve which are enabled by nuclear power.
Bents, David J. +2 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Cross-Domain Fault Diagnosis Using Knowledge Transfer Strategy: A Review
IEEE Access, 2019 Data-driven fault diagnosis has been a hot topic in recent years with the development of machine learning techniques. However, the prerequisite that the training data and the test data should follow an identical distribution prevents the conventional ...
Huailiang Zheng +6 more
doaj +1 more source
A Flexible Path for Human and Robotic Space Exploration [PDF]
, 2010 David Korsmeyer +5 more
openalex +1 more source
Exploration for fossil and nuclear fuels from orbital altitudes [PDF]
Results from the ERTS program pertinent to exploration for oil, gas, and uranium are discussed. A review of achievements in relevant geological studies from ERTS, and a survey of accomplishments oriented towards exploration for energy sources are ...
Short, N. M.
core +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
The use of acoustics in space exploration
, 2007 In recent years increased attention has been paid to the potential uses of acoustics forextraterrestrial exploration. The extent to which acoustics per se is used in these studiesvaries greatly. First, there are the cases in which acoustics is simply the
Leighton, T.G.
core
Hierarchical Exploration for Accelerating Contextual Bandits [PDF]
, 2012 Contextual bandit learning is an increasingly popular approach to optimizing recommender systems via user feedback, but can be slow to converge in practice due to the need for exploring a large feature space.
Guestrin, Carlos +2 more
core +1 more source