Results 61 to 70 of about 6,891,830 (344)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Heat Semigroup on Configuration Spaces
Publications of the Research Institute for Mathematical Sciences, 2003 In this paper, we study properties of the heat semigroup of configuration space analysis. Using a natural “Riemannian-like” structure of the configuration space Γ_X over a complete, connected, oriented, and stochastically complete Riemannian ...
Kondratiev, Yuri +2 more
openaire +4 more sources
ThermoEnergy transition is a challenge for remote northern communities mainly relying on diesel for electricity generation and space heating. Solar-assisted ground-coupled heat pump (SAGCHP) systems represent an alternative that was investigated in this study ...
Alice Cavalerie +4 more
doaj +1 more source
Instability Heating of Sympathetically-Cooled Ions in a Linear Paul Trap [PDF]
, 2002 Sympathetic laser cooling of ions stored within a linear-geometry, radio frequency, electric-quadrupole trap has been investigated using computational and theoretical techniques. The simulation, which allows 5 sample ions to interact with 35 laser-cooled
A. C. Truscott +18 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Sustainability, 2020 In the near future, renewable energy sources (RES) will make up an increasing share of energy production in the district heating grid, implying that utilities must enable energy flexibility in order to compensate for the intermittent nature of RES ...
Simon Peter Aslak Kondrup Larsen +1 more
semanticscholar +1 more source
Economic Feasibility of North Slope Propane Production and Distribution to Select Alaska Communities [PDF]
, 2010 Could propane from Alaska’s North Slope reduce energy costs for electric utilities and residential space heating, water heating, and cooking demands? We explored the hypothesis that propane is a viable alternative for fourteen selected communities along ...
Fay, Ginny, Schwörer, Tobias
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Compression of Atomic Phase Space Using an Asymmetric One-Way Barrier
, 2005 We show how to construct asymmetric optical barriers for atoms. These barriers can be used to compress phase space of a sample by creating a confined region in space where atoms can accumulate with heating at the single photon recoil level. We illustrate
A. M. Dudarev +5 more
core +1 more source