Results 71 to 80 of about 10,625,611 (286)

Advanced exergy-based performance enhancement of heat pump space heating system

open access: yesEnergy, 2020
Heat pump technologies for space heating can contribute to substantial economic, environmental and energy saving benefits. However, their performance is generally evaluated through energy-based methods.
V. Voloshchuk, P. Gullo, V. Sereda
semanticscholar   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Conservatories and domestic heating [PDF]

open access: yes, 1987
Passive solar gains to buildings in North European Climates can be significant and an investigation is made into the effect of orientation upon solar gains based upon known weather data.
Felgate, G.B.
core   +5 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Financial and Energetic Optimization of Greek Buildings Insulation

open access: yesDesigns, 2018
The most important parameter in the design of the building envelope is the insulation thickness, because it dramatically influences the heating and cooling loads.
Georgios Mitsopoulos   +2 more
doaj   +1 more source

Economic model predictive control of space heating and dynamic solar shading

open access: yes, 2020
Dynamic solar shading devices are an effective mean to avoid overheating in buildings due to excessive solar heat gains. They can also be used to affect the heat balance of buildings; they can be on e.g.
M. Knudsen, S. Petersen
semanticscholar   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

The American Society of Heating and Ventilating Engineers Guide

open access: yes, 1922
The purpose of the American Society of Heating and Ventilating Engineers Guide is to provide the engineer, the architect and the contractor alike, with a useful and reliable reference data book relating to the art of heating and ventilation. A wide range
American Society of Heating and Ventilating Engineers
core   +3 more sources

New insights into thermal comfort sufficiency in dwellings

open access: yesBuildings & Cities
Domestic heating is a major contributor to energy consumption and must be minimised to achieve climate targets. Building on the concept of addressing the distinct heating needs of individuals and buildings separately, the Slowheat project implemented a ...
Geoffrey van Moeseke   +4 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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