Results 71 to 80 of about 30,463 (266)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Direct Utilization of Geothermal Energy

Energies, 2010
The worldwide application of geothermal energy for direct utilization is reviewed. This paper is based on the world update for direct-use presented at the World Geothermal Congress 2010 in Bali, Indonesia (WGC2010) [1] which also includes material ...
John W. Lund
doaj   +1 more source

Green Hypocrisy?: Environmental Attitudes and Residential Space Heating Expenditure [PDF]

, 2012
In the UK, the largest proportion of household energy use is for space heating. Popular media make claims of a green hypocrisy: groups which have the strongest attitude towards the environment have the highest emissions.
Traynor, Laura, Lange, Ian, Moro, Mirko, Lange, Ian A.   +3 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Model Analysis of Solar Thermal System with the Effect of Dust Deposition on the Collectors

Energies, 2018
In this study, a TraNsient SYStems (TRNSYS) simulation model for solar thermal systems is developed to assess the potential of solar energy utilization in cold climate zones, such as Ulaanbaatar (Mongolia), which is one of the five cities with the worst ...
Purevdalai Erdenedavaa, Antonio Rosato, Amarbayar Adiyabat, Atsushi Akisawa, Sergio Sibilio, Antonio Ciervo   +5 more
doaj   +1 more source

Statistical signature of active D-region HF heating in IRIS riometer data from 1994-2004 [PDF]

, 2007
International audienceIn this paper we study the effect of artificial HF heating on cosmic radio noise absorption in the D-region ionosphere. The effect has earlier been studied theoretically in idealised cases and without experimental verification. Here
F. H. Honary, Rietveld, Michael T., Ulich, T., C.-F. Enell, Enell, C.-F., Honary, F., Rietveld, M. T., A. Kero, E. Turunen, Honary, F. H., Ulich, Th., M. T. Rietveld, Turunen, E., Th. Ulich, Kero, A.   +14 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A New Mixture Refrigerant for Space Heating Air Source Heat Pump: Theoretical Modelling and Performance Analysis

Applied Sciences, 2018
Air source heat pump (ASHP) is becoming a substitute for small coal boilers in rural residential buildings of North China. However, the application of ASHP faces challenges of heating capacity, energy efficiency, ozone depletion potential (ODP) and ...
Xiangrui Kong, Yufeng Zhang, Jinzhe Nie
doaj   +1 more source

Estimating thermal energy loads in remote and northern communities to facilitate a net-zero transition

Environmental Research: Infrastructure and Sustainability, 2023
Canada has more than 350 remote and northern communities, most of which rely on diesel for their electric and thermal needs. This reliance is deleterious to climate, health, albedo, and energy security—all diesel must be imported.
Ian Maynard, Ahmed Abdulla
doaj   +1 more source

Study of the Heating Load of a Manufactured Space with a Gas-fired Radiant Heating System [PDF]

, 2006
A thermal balance mathematics model of a manufactured space with a gas-fired radiant heating system is established to calculate the heating load. Computer programs are used to solve the model.
Dong, Z., Zheng, X.
core