Results 51 to 60 of about 5,022 (266)

Quasithermal Noise in Magnetized Plasma: Theory and Simulations

The Astrophysical Journal
Quasithermal noise (QTN) spectroscopy has been extensively used as an accurate tool to measure electron density and temperature in unmagnetized space plasmas. The observed spectrum depends on both antenna geometry and plasma kinetic properties.
Xianming Zheng, Mihailo M. Martinović, Kristopher G. Klein, Viviane Pierrard, Mingzhe Liu, Xianghui Xue, Shi Tao, Kun Cheng, Han Wu, Bingkun Yu   +9 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Direct evidence of substorm-related impulsive injections of electrons at Mercury

Nature Communications, 2023
Mercury’s magnetosphere is known to involve fundamental processes releasing particles and energy like at Earth due to the solar wind interaction. The resulting cycle is however much faster and involves acceleration, transport, loss, and recycling of ...
Sae Aizawa, Yuki Harada, Nicolas André, Yoshifumi Saito, Stas Barabash, Dominique Delcourt, Jean-André Sauvaud, Alain Barthe, Andréi Fedorov, Emmanuel Penou, Shoichiro Yokota, Wataru Miyake, Moa Persson, Quentin Nénon, Mathias Rojo, Yoshifumi Futaana, Kazushi Asamura, Manabu Shimoyama, Lina Z. Hadid, Dominique Fontaine, Bruno Katra, Markus Fraenz, Norbert Krupp, Shoya Matsuda, Go Murakami   +24 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Local Transition of Electron Pitch Angle Distribution within Flux Pileup Region behind Dipolarization Front

The Astrophysical Journal
Dipolarization fronts (DFs), earthward-propagating magnetic transients with a strong magnetic field, are important regions favorable for energetic electron acceleration in the magnetotail.
X. N. Xing, C. M. Liu, J. B. Cao, Y. Y. Liu, B. N. Zhao   +4 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Periodically Modulated Magnetic Reconnection

The Astrophysical Journal
We present the first evidence for periodically modulated reconnection at the electron scale in space, using unparalleled, high-cadence data from Magnetospheric Multiscale spacecraft.
Chengming Liu, Jinbin Cao, Xining Xing, Yangyang Liu, Boning Zhao   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source