Results 101 to 110 of about 5,668,523 (337)

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Suited for spacewalking: A teacher's guide with activities [PDF]

open access: yes, 1992
This publication is an activity guide for teachers on spacesuits and spacewalking. It uses the intensive interest many children have in space exploration as a launching point for hands-on-opportunities.
Manning, Cheryl A., Vogt, Gregory L.
core   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Earth's Atmospheric Electricity Parameter Response During Venus Transit

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
Venus transited across the Sun on 06 June 2012, introducing significant contribution to the tidal characteristics of the solar atmosphere. _ atmosphere was perturbed due to an anomalous Coronal Mass Ejection (CME) and γ-radiationγ-radiation influenced by
Syam Sundar De   +4 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Lower Mantle Electrical Conductivity Inferred from Probabilistic Tomography

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
Electrical conductivity is a potentially powerful observable that may be used in combination with seismological models to investigate the 3D thermo-chemical structure of the _ mantle because it depends upon both temperature and compositional parameters ...
Frédéric Deschamps
doaj   +1 more source

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