Results 111 to 120 of about 5,668,523 (337)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The Crustal Thickness of the Philippine Sea Plate Derived from Gravity Data

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
We constructed a new free-air gravity anomaly map of the Philippine Sea Plate (PSP) using ship-tracked gravity data from the National Geophysical Data Center (NGDC).
Horng-Yuan Yen   +7 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Space Science and Technology Education, Teaching, Research. [PDF]

open access: yesSpace Policy, 2020
Haubold HJ, Mathai AM, Pyenson L.
europepmc   +1 more source

Space Science at the University of Rochester [PDF]

open access: bronze, 1962
D Karl   +8 more
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

An Evaluation of the Mellor-Yamada-Janjić Formulation Parameters for the QNSE Scheme in the WRF Model over the Lower Yangtze River Valley

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
Accurate description of boundary layer processes is important for numerical simulations, and some model parameters in the boundary layer schemes play an important role in the model simulations.
Huiyan Xu   +4 more
doaj   +1 more source

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