Results 111 to 120 of about 8,495,084 (302)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Polar Research, 2017 The sociality of the Arctic fox has been extensively studied during the breeding season, so that its summer territorial and generally monogamous social systems are now well described.
Marie-Jeanne Rioux +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A Forward Branching Phase-Space Generator
, 2011 We develop a forward branching phase-space generator for use in next-to-leading order parton level event generators. By performing 2 -> 3 branchings from a fixed jet phase-space point, all bremsstrahlung events contributing to the given jet configuration
Giele, Walter T. +2 more
core
Public and private use of open space in a densely urbanized context [PDF]
, 2010 The boundary between the Flemish urban and rural areas has faded in recent years and a fragmented spatial structure has emerged. The ‘open space’ is evolving from an agricultural production area to a semi-urbanized consumption area.
Allaert, Georges +4 more
core +1 more source
Articulatory Oral Space Measures Using the Modified A-Space
, 2007 The X-ray microbeam method for measurement of articulatory dynamics has been used to acquire large amounts of data, with reduced X-ray dosage, resulting in one of the most widely used freely available speech production databases. The X-ray Microbeam Speech Production Database (XRMB-SPD), developed at Wisconsin University, USA, includes a vast amount of
Jesus, Luís M. T. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Space station models, mockups and simulators [PDF]
, 1985 Schematic outlines for space station models, mockups, and simulators are presented. The types of Boeing models, mockups, and simulators are given along with the classes and characteristics.
Miller, K. H., Osgood, A.
core +1 more source