Results 101 to 110 of about 1,307,984 (295)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Prevalence of Oral Complications in Head The Effect of Spacing with Applying Wax on Abutment, on the Retention of Implant Supported Crowns Luted With Different Types of Temporary Cements

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2007
Introduction: Some technicians in dental laboratories of Iran have used wax as spacer in implant prosthesis fabrications. This study evaluated the effect of two methods of applying spacer on the retention of implant supported single crowns by using three
A Hafezeqoran, H Sazgara, F Tabatabai
doaj  

Low incidence of significant hydrogel spacer rectal wall infiltration: results from an experienced high-volume center

open access: yesFrontiers in Oncology
ObjectivesTo evaluate the incidence and degree of rectal wall infiltration (RWI) of spacer gel used during prostate radiotherapy among two practitioners experienced in using rectal spacers.Materials and methodsConsecutive patients with prostate cancer ...
Sungmin Woo   +8 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Biomechanical Analysis of a spacer for knee neoplasms in terms of resection extension by means of finite elements

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2013
When knee bony tumors appear, arthrodesis is one terapeutic option after tumor block resection. The implant is composed of an intramedular nail with four interlocking pins. The whole implant is manufactured using a titanium alloy (Ti-6Al-4V). The spacer
Víctor Araujo   +7 more
doaj  

The Innovative Design and Performance Testing of a Mobile Robot for the Automated Installation of Spacers on Six-Split Transmission Lines

open access: yesMachines
The spacer is an important component of a transmission line and can effectively prevent wires from whipping each other and inhibit vibration. Given the complex installation conditions of multi-split lines, the installation of spacers is mainly achieved ...
Jie Pan   +6 more
doaj   +1 more source

Tissue engineering of cartilage in space

open access: green, 1997
Lisa E. Freed   +4 more
openalex   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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