Results 111 to 120 of about 1,182,202 (280)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Directivity and spacing for the antenna elements [PDF]
The optimum design choice for the MST radar antenna was considered. The following factors are required: directivity and gain; beam width and its symmetry; sidelobe levels, near and wide angle; impedance matching; feeder network losses; polarization ...
Koshy, V. K.
core +1 more source
Dual spaces of weighted spaces [PDF]
The topological duals of a large class of weighted spaces of continuous functions are characterized as spaces of Radon measures which can be factored into a product of a weight function and a bounded Radon measure. We next obtain a representation for a base for the equicontinuous subsets of these dual spaces and for the extremal points of the members ...
openaire +2 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Crop growth models have been considered as potential tools for simulating growth and yield of crops. Hence, Decision Support System for Agro-technology Transfer/Crop Estimation through Resource and Environment Synthesis (DSSAT v 4.5/CERES-Rice) model ...
ANCHAL DASS +3 more
doaj +1 more source
Extremal Colorings and Independent Sets [PDF]
We consider several extremal problems of maximizing the number of colorings and independent sets in some graph families with fixed chromatic number and order.
Engbers, John, Erey, Aysel
core +1 more source
Covering spaces of paracompact spaces [PDF]
This note proves that in the context of paracompact spaces, a definition used by the author implies the definition used by Saul Lubkin which does not involve the usual connectedness properties associated with covering spaces.
openaire +2 more sources
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

