Results 111 to 120 of about 1,182,202 (280)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Directivity and spacing for the antenna elements [PDF]

open access: yes, 1983
The optimum design choice for the MST radar antenna was considered. The following factors are required: directivity and gain; beam width and its symmetry; sidelobe levels, near and wide angle; impedance matching; feeder network losses; polarization ...
Koshy, V. K.
core   +1 more source

Dual spaces of weighted spaces [PDF]

open access: yesTransactions of the American Mathematical Society, 1970
The topological duals of a large class of weighted spaces of continuous functions are characterized as spaces of Radon measures which can be factored into a product of a weight function and a bounded Radon measure. We next obtain a representation for a base for the equicontinuous subsets of these dual spaces and for the extremal points of the members ...
openaire   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Simulation of maturity duration and productivity of two rice varieties under system of rice intensification using DSSAT v 4.5/CERES-Rice model

open access: yesJournal of Agrometeorology, 2012
Crop growth models have been considered as potential tools for simulating growth and yield of crops. Hence, Decision Support System for Agro-technology Transfer/Crop Estimation through Resource and Environment Synthesis (DSSAT v 4.5/CERES-Rice) model ...
ANCHAL DASS   +3 more
doaj   +1 more source

Extremal Colorings and Independent Sets [PDF]

open access: yes, 2018
We consider several extremal problems of maximizing the number of colorings and independent sets in some graph families with fixed chromatic number and order.
Engbers, John, Erey, Aysel
core   +1 more source

Covering spaces of paracompact spaces [PDF]

open access: yesProceedings of the American Mathematical Society, 1975
This note proves that in the context of paracompact spaces, a definition used by the author implies the definition used by Saul Lubkin which does not involve the usual connectedness properties associated with covering spaces.
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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