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Performance of Active-Quenching SPAD Array Based on the Tri-State Gates of FPGA and Packaged with Bare Chip Stacking [PDF]

open access: yesSensors, 2023
The performance of an active-quenching single-photon avalanche diode (SPAD) array that is based on the tri-state gates of a field programmable gate array (FPGA) is presented.
Liangliang Liu   +6 more
doaj   +5 more sources

First-Arrival Differential Counting for SPAD Array Design [PDF]

open access: yesSensors, 2023
We present a novel architecture for the design of single-photon detecting arrays that captures relative intensity or timing information from a scene, rather than absolute. The proposed method for capturing relative information between pixels or groups of
Mel White   +5 more
doaj   +7 more sources

Confocal-based fluorescence fluctuation spectroscopy with a SPAD array detector [PDF]

open access: yesLight: Science & Applications, 2021
The combination of confocal laser-scanning microscopy (CLSM) and fluorescence fluctuation spectroscopy (FFS) is a powerful tool in studying fast, sub-resolution biomolecular processes in living cells.
Eli Slenders   +7 more
doaj   +8 more sources

Advantages and Limitations of Fluorescence Lifetime Measurements Using Single-Photon Avalanche Diode (SPAD) Array Detector: A Comprehensive Theoretical and Experimental Study [PDF]

open access: yesSensors, 2022
Fast fluorescence lifetime (FL) determination is a major factor for studying dynamic processes. To achieve a required precision and accuracy a certain number of photon counts must be detected.
Alexander Netaev   +2 more
doaj   +5 more sources

Demonstration of particle tracking with scintillating fibres read out by a SPAD array sensor and application as a neutrino active target [PDF]

open access: yesEuropean Physical Journal C: Particles and Fields, 2023
Scintillating fibre detectors combine sub-mm resolution particle tracking, precise measurements of the particle stopping power and sub-ns time resolution. Typically, fibres are read out with silicon photomultipliers (SiPM).
Matthew Franks   +11 more
doaj   +4 more sources

Cooled SPAD array detector for low light-dose fluorescence laser scanning microscopy [PDF]

open access: yesBiophysical Reports, 2021
The single-photon timing and sensitivity performance and the imaging ability of asynchronous-readout single-photon avalanche diode (SPAD) array detectors have opened up enormous perspectives in fluorescence (lifetime) laser scanning microscopy (FLSM ...
Eli Slenders   +11 more
doaj   +3 more sources

Design and Characterization of an Asynchronous Fixed Priority Tree Arbiter for SPAD Array Readout [PDF]

open access: yesSensors, 2021
The usage of single-photon avalanche diode arrays is becoming increasingly common in various domains such as medical imaging, automotive vision systems, and optical communications. Nowadays, thanks to the development of microelectronics technologies, the
Enagnon Aguénounon   +8 more
doaj   +4 more sources

A time-correlated single photon counting SPAD array camera with a bespoke data-processing algorithm for lightsheet fluorescence lifetime imaging (FLIM) and FLIM videos [PDF]

open access: yesScientific Reports
A wide-field microscope with epi-fluorescence and selective plane illumination was combined with a single-photon avalanche diode (SPAD) array camera to enable live-cell fluorescence lifetime imaging (FLIM) using time-correlated single-photon counting ...
Jakub Nedbal   +7 more
doaj   +3 more sources

Multispectral Depth-Resolved Fluorescence Lifetime Spectroscopy Using SPAD Array Detectors and Fiber Probes [PDF]

open access: yesSensors, 2019
Single Photon Avalanche Diode (SPAD) arrays are increasingly exploited and have demonstrated potential in biochemical and biomedical research, both for imaging and single-point spectroscopy applications. In this study, we explore the application of SPADs
João L. Lagarto   +7 more
doaj   +4 more sources

Cerebral blood flow monitoring using a deep learning implementation of the two-layer diffuse correlation spectroscopy analytical model with a 512 × 512 SPAD array. [PDF]

open access: yesNeurophotonics
. Significance Multilayer (two- and three-layer) diffuse correlation spectroscopy (DCS) models improve cerebral blood flow index (CBFi) measurement sensitivity and mitigate interference from extracerebral tissues.
Pan M   +10 more
europepmc   +3 more sources

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