Results 51 to 60 of about 213,065 (277)

Investigating the type 2 diabetes epidemic and contributing lifestyle factors in the State of Kuwait: an evolutionary mismatch perspective

Academia Nutrition and Dietetics
Diabetes mellitus is a complex, multifactorial group of chronic metabolic diseases falling under the umbrella of non-communicable diseases. In the State of Kuwait, the prevalence of diabetes mellitus is 22.4% among men and 14.4% among women ...
Wesley Kuijpers
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Field‐Assisted Sintering Technology/Spark Plasma Sintering: Mechanisms, Materials, and Technology Developments

, 2014
Field‐assisted sintering technology/Spark plasma sintering is a low voltage, direct current (DC) pulsed current activated, pressure‐assisted sintering, and synthesis technique, which has been widely applied for materials processing in the recent years ...
O. Guillon, J. Gonzalez‐Julian, Benjamin Dargatz, T. Kessel, G. Schierning, J. Räthel, M. Herrmann   +6 more
semanticscholar   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Data leakage in deep learning studies of translational EEG

Frontiers in Neuroscience
A growing number of studies apply deep neural networks (DNNs) to recordings of human electroencephalography (EEG) to identify a range of disorders. In many studies, EEG recordings are split into segments, and each segment is randomly assigned to the ...
Geoffrey Brookshire, Jake Kasper, Nicholas M. Blauch, Nicholas M. Blauch, Yunan Charles Wu, Ryan Glatt, David A. Merrill, David A. Merrill, David A. Merrill, Spencer Gerrol, Keith J. Yoder, Colin Quirk, Ché Lucero   +12 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

News Text Topic Clustering Optimized Method Based on TF-IDF Algorithm on Spark

Computers Materials & Continua, 2020
: Due to the slow processing speed of text topic clustering in stand-alone architecture under the background of big data, this paper takes news text as the research object and proposes LDA text topic clustering algorithm based on Spark big data platform.
Zhuo Zhou, Jiaohua Qin, Xuyu Xiang, Yun Tan, Qiang Liu, Neal N. Xiong   +5 more
semanticscholar   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors

Pharmacology Research & Perspectives
G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an
Catherine J. Hutchings, Serbülent Ünsal, Mathieu Rappas, Matthew Barnes, Maria Waldhoer, Ben Holland, Martin Culka   +6 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source