Results 81 to 90 of about 213,065 (277)
Electric machine performance can be enhanced through torque ripple mitigation, which reduces mechanical vibrations and improves system stability and operation.
Ali Mohammadi +3 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Measuring electrophysiological changes induced by sub-concussive impacts due to soccer ball heading
A growing body of research suggests that impacts to the head, including sub-concussive impacts, carry risks for long-term detrimental effects on cognition and brain health.
Geoffrey Brookshire +16 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
An Overview of Silica Scaling Reduction Technologies in the Geothermal Market
Renewable energy sources play a vital role in the energy mix with geothermal energy providing an opportunity to harness the natural heat coming from the Earth for sustainable power production.
Rochelle Longval +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Disasters (natural or man-made) can be lethal to human life, the environment, and infrastructure. The recent advancements in the Internet of Things (IoT) and the evolution in big data analytics (BDA) technologies have provided an open opportunity to ...
Syed Attique Shah +5 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The contribution of the private sector to solutions for displacement
The Solutions Alliance is exploring ways of better engaging with the private sector – local small and medium-sized enterprises as well as international companies – to harness their capacity to turn displacement challenges into development opportunities.
Glaucia Boyer, Yannick DuPont
doaj

