Results 41 to 50 of about 61,567 (256)

Hydrodynamic parameters of air-bubble stimulated underwater spark discharges [PDF]

open access: yes, 2017
Considerable amount of research work has been focused on investigation and optimization of strong acoustic waves generated by spark discharges in water.
Bonifaci, N.   +7 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Study on Evaluation Method of Impulse Dispersion Performance of Grounding Device Using X-ray Imagining System

open access: yesEnergies, 2021
When the lightning current enters the ground through the grounding system, the impulse dispersion performance can be observed by the phenomenon of soil spark discharge, which is fundamentally determined by the nearby soil.
Xiaoyan Han   +5 more
doaj   +1 more source

Probing photo-ionization: Experiments on positive streamers in pure gasses and mixtures [PDF]

open access: yes, 2010
Positive streamers are thought to propagate by photo-ionization whose parameters depend on the nitrogen:oxygen ratio. Therefore we study streamers in nitrogen with 20%, 0.2% and 0.01% oxygen and in pure nitrogen, as well as in pure oxygen and argon.
  +43 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Influences of discharge modes and gas bubbling conditions on E. coli sterilization by pulsed underwater discharge treatments

open access: yesAIP Advances, 2020
Underwater discharges are considered to be promising solutions to water disinfection problems. In this paper, the sterilization effects of different discharge modes and gas bubbling conditions on E. coli are investigated.
Yuan Li   +4 more
doaj   +1 more source

Laboratory studies of spacecraft response to transient discharge pulses [PDF]

open access: yes, 1985
The in-orbit measurement of spacecraft discharge properties was investigated. The experiments include design and fabrication of appropriate sensors and effects of spacecraft electromagnetic responses on the interpretation of the discharge data.
Adamo, R. C., Nanevicz, J. E.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Investigation of the Scanning Microarc Oxidation Process [PDF]

open access: yes, 2017
Scanning microarc oxidation (SMAO) is a coating process which is based on conventional microarc oxidation (MAO). The key difference is that deposition in SMAO is achieved by using a stainless steel nozzle to spray an electrolyte stream on the substrate ...
Domblesky, Joseph P.   +4 more
core   +3 more sources

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