Results 151 to 160 of about 29,371 (197)
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Hereditary spastic paraparesis and psychosis
European Journal of Neurology, 2006Hereditary spastic paraparesis (HSP) is characterized by progressive spasticity and weakness of the legs with or without additional abnormalities. Reports of psychiatric disorders in patients with HSP are limited to mood disturbances rather than to psychosis. We had noted significant psychotic illness in several patients recruited to a survey of HSP in
P, McMonagle, M, Hutchinson, B, Lawlor
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Neurology, 1985
Adrenoleukodystrophy (ALD) must be considered in the diagnosis of men with progressive nervous system disease. We found the biochemical defect characteristic of ALD in two brothers with spastic paraparesis of late adult onset. Family study then revealed other affected men and asymptomatic heterozygotes in a pattern that conformed to an X-linked pattern
B P, O'Neill +4 more
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Adrenoleukodystrophy (ALD) must be considered in the diagnosis of men with progressive nervous system disease. We found the biochemical defect characteristic of ALD in two brothers with spastic paraparesis of late adult onset. Family study then revealed other affected men and asymptomatic heterozygotes in a pattern that conformed to an X-linked pattern
B P, O'Neill +4 more
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The Neurourology of Tropical Spastic Paraparesis
British Journal of Urology, 1991Summary— We report the clinical features, urodynamic results and neurophysiological findings in 6 patients with urinary symptoms related to tropical spastic paraplegia. The widespread nature of the pathological changes within the nervous system result in a complex variety of urodynamic and neurophysiological ...
I, Eardley +4 more
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Tropical spastic paraparesis in colombia
Annals of Neurology, 1988A high-incidence focus of tropical spastic paraparesis (TSP) occurs on the South Pacific coast of Colombia. Of 55 patients studied, 52 (94.5%) had IgG antibodies to the human T-cell lymphotropic virus type I (HTLV-I) in serum and/or cerebrospinal fluid. Control groups did not show similar high positivity.
Vladimir Zaninovic +11 more
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Progressive Spastic Paraparesis
Archives of Neurology, 1977To the Editor.— Relative to the article "Progressive Spastic Paraparesis and Adrenal Insufficiency" by Gumbinas and associates published in the October issue of theArchives(33:678, 1976), I take the liberty to add that in the article "Atrophie idiopathique des surrenales et sclerose combinee de la moelle epiniere" by M. Bedivan, A.
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Spastic paraparesis and sensory neuropathy
Muscle & Nerve, 1992A 12-year-old developed a slowly progressive spastic gait at the age of 3. A marked loss of pain and temperature sensations led to a mutilating acropathy starting at age 5. Electrodiagnostic studies revealed a symmetric, axonal, predominantly sensory neuropathy, and magnetic resonance imaging ruled out compression of spinal cord.
S N, Tenembaum +3 more
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The neuroepidemiology of tropical spastic paraparesis
Annals of Neurology, 1988Recent neuroepidemiological studies of endemic tropical spastic paraparesis (TSP) have confirmed the existence of high-prevalence foci in several tropical islands, including Jamaica and Martinique in the Caribbean, Tumaco off the Pacific coast of Colombia, and the Seychelles in the Indian Ocean.
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Progressive Spastic Paraparesis and Adrenal Insufficiency
Archives of Neurology, 1976A 10-year-old boy with progressive paraparesis, personality change, and seizures had laboratory evidence of adrenal insufficiency. Pathologic study showed cerebral edema, but no loss of myelin. Notable pathologic changes were limited to the spinal cord, where the corticospinal and spinocerebellar tracts were demyelinated.
M, Gumbinas +4 more
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Spastic paraparesis as a manifestation of Leber’s disease
Journal of Neurology, 2005Sirs: Leber’s hereditary optic neuropathy (LHON) is a genetic disease due to mutations in mitochondrial DNA (mtDNA) responsible for central, bilateral, painless, and fast progressive visual loss with optic nerve atrophy. Various extra-ocular manifestations, called Leber’s “plus” syndrome, have been described [4].
Frédéric, Clarençon +7 more
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Immunological studies in tropical spastic paraparesis
Annals of Neurology, 1990AbstractTropical spastic paraparesis (TSP) and other chronic‐progressive myelopathies have been clearly associated with increased serum and cerebrospinal fluid antibody titers to human T‐lymphotropic virus type I (HTLV‐I). However, little is known about the cellular immune function in TSP. In the present study, activated T lymphocytes were found in the
S, Jacobson +4 more
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