Results 161 to 170 of about 10,460 (201)

Tropical spastic paraparesis in colombia

Annals of Neurology, 1988
A high-incidence focus of tropical spastic paraparesis (TSP) occurs on the South Pacific coast of Colombia. Of 55 patients studied, 52 (94.5%) had IgG antibodies to the human T-cell lymphotropic virus type I (HTLV-I) in serum and/or cerebrospinal fluid. Control groups did not show similar high positivity.
Vladimir Zaninovic, Cesar Arango, Robin Biojo, Carios Mora, Pamela Rodgers-Johnson, Mauricio Concha, Raul Corral, Pablo Barreto, Isabella Borrero, Ralph M. Garruto, Clarence J. Gibbs, D. Carleton Gajdusek   +11 more
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The neuroepidemiology of tropical spastic paraparesis

Annals of Neurology, 1988
Recent neuroepidemiological studies of endemic tropical spastic paraparesis (TSP) have confirmed the existence of high-prevalence foci in several tropical islands, including Jamaica and Martinique in the Caribbean, Tumaco off the Pacific coast of Colombia, and the Seychelles in the Indian Ocean.
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Spastic paraparesis as a manifestation of Leber’s disease

Journal of Neurology, 2005
Sirs: Leber’s hereditary optic neuropathy (LHON) is a genetic disease due to mutations in mitochondrial DNA (mtDNA) responsible for central, bilateral, painless, and fast progressive visual loss with optic nerve atrophy. Various extra-ocular manifestations, called Leber’s “plus” syndrome, have been described [4].
Frédéric, Clarençon, Emmanuel, Touzé, Anne, Leroy-Willig, Hélène, Turmel, Olivier, Naggara, Stéphane, Pavy, Antoine, Brézin, Jean-Louis, Mas   +7 more
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Immunological studies in tropical spastic paraparesis

Annals of Neurology, 1990
AbstractTropical spastic paraparesis (TSP) and other chronic‐progressive myelopathies have been clearly associated with increased serum and cerebrospinal fluid antibody titers to human T‐lymphotropic virus type I (HTLV‐I). However, little is known about the cellular immune function in TSP. In the present study, activated T lymphocytes were found in the
S, Jacobson, A, Gupta, D, Mattson, E, Mingioli, D E, McFarlin   +4 more
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The Effects of Dalfampridine on Hereditary Spastic Paraparesis

European Neurology, 2016
[No abstract available]
Uygunoglu, Ugur, Gunduz, Aysegul, Tutuncu, Melih, Akalin, Mehmet Ali, Saip, Sabahattin, Siva, Aksel   +5 more
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Progressive Spastic Paraparesis and Adrenal Insufficiency

Archives of Neurology, 1976
A 10-year-old boy with progressive paraparesis, personality change, and seizures had laboratory evidence of adrenal insufficiency. Pathologic study showed cerebral edema, but no loss of myelin. Notable pathologic changes were limited to the spinal cord, where the corticospinal and spinocerebellar tracts were demyelinated.
M, Gumbinas, H M, Liu, G, Dawson, M, Larsen, O, Green   +4 more
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Tropical Spastic Paraparesis

Archives of Neurology, 2001
T ropical spastic paraparesis (TSP), a progressive myelopathy predominantly affecting the lower limbs, is currently synonymous with human T-lymphotropic virus type I (HTLVI)–associated myelopathy/tropical spastic paraparesis (HAM/TSP). At the turn of the 20th century, Drs Henry Strachan and Henry Scott provided the first clinical descriptions of ...
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Chapter 17 Hereditary spastic paraparesis

2007
Publisher Summary Hereditary spastic paraparesis (HSP) represents a group of conditions in which the prominent feature is a progressive spastic paraparesis. The most useful way of classifying HSP is genetically to one of the current HSP gene loci. There are currently 28 spastic paraplegia (SPG) loci.
Christopher J, McDermott, Pamela J, Shaw
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Clonus Associated with Tropical Spastic Paraparesis

New England Journal of Medicine, 2016
A 53-year-old woman with tropical spastic paraparesis reported several months of worsening weakness of the legs and feet. On examination, she had severe spasticity and weakness of both legs and feet, bilateral Babinski sign, and bilateral patellar clonus, shown in a video.
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Spastic Paraparesis of Insidious Onset

Hospital Practice, 1994
A, Adlakha, H J, Schultz
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