Results 91 to 100 of about 166,105 (376)

Development of a simple mechanical measurement method to measure spasticity based on an analysis of a clinical maneuver and its concurrent validity with the modified Ashworth scale

Frontiers in Bioengineering and Biotechnology, 2022
Background: Despite recent developments in the methodology for measuring spasticity, the discriminative capacity of clinically diagnosed spasticity has not been well established.
Hiroki Tanikawa, Masahiko Mukaino, Shota Itoh, Hikaru Kondoh, Kenta Fujimura, Toshio Teranishi, Kei Ohtsuka, Satoshi Hirano, Hitoshi Kagaya, Eiichi Saitoh, Yohei Otaka   +10 more
doaj   +1 more source

Evaluation of the electro-dress Mollii® to affect spasticity and motor function in children with cerebral palsy: Seven experimental single-case studies with an ABAB design [PDF]

, 2022
Marina Arkkukangas, Jenny Hedberg‐Graff, Eva Denison   +2 more
openalex   +1 more source

Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis. [PDF]

, 2012
This study investigated the antispasticity potential of Sativex in mice. Chronic relapsing experimental allergic encephalomyelitis was induced in adult ABH mice resulting in hind limb spasticity development.
Al-Izki, S, Bolton, C, Giovannoni, G, Guy, G, Hilliard, A, Pryce, G, Stott, C, Wright, S   +7 more
core   +2 more sources

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Functional Brain Correlates of Upper Limb Spasticity and Its Mitigation following Rehabilitation in Chronic Stroke Survivors

Stroke Research and Treatment, 2014
Background. Arm spasticity is a challenge in the care of chronic stroke survivors with motor deficits. In order to advance spasticity treatments, a better understanding of the mechanism of spasticity-related neuroplasticity is needed. Objective.
Svetlana Pundik, Adam D. Falchook, Jessica McCabe, Krisanne Litinas, Janis J. Daly   +4 more
doaj   +1 more source

Interventions for improving upper limb function after stroke [PDF]

, 2013
Background: Improving upper limb function is a core element of stroke rehabilitation needed to maximise patient outcomes and reduce disability. Evidence about effects of individual treatment techniques and modalities is synthesised within many reviews ...
Brady, Marian C., Farmer, Sybil E., Langhorne, Peter, Mead, Gillian E., Mehrholz, Jan, Pollock, Alex, van Wijck, Frederike   +6 more
core   +3 more sources

A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus

Advanced Science, EarlyView.
A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang, Chaohua Fang, Ruoyu Sun, Chenghao Feng, Xiaoyuan Wang, Hao Bi, Yidan Wu, Jiangdong Gong, Yuyang Wang, Jiahao Guo, Yu Chang, Huizhi Wang, Tingrui Pan   +12 more
wiley   +1 more source

Motor Overflow and Spasticity in Chronic Stroke Share a Common Pathophysiological Process: Analysis of Within-Limb and Between-Limb EMG-EMG Coherence

Frontiers in Neurology, 2018
The phenomenon of exaggerated motor overflow is well documented in stroke survivors with spasticity. However, the mechanism underlying the abnormal motor overflow remains unclear.
Yen-Ting Chen, Sheng Li, E. Magat, P. Zhou, Sheng Li   +4 more
semanticscholar   +1 more source

Infantile‐Onset Ascending Hereditary Spastic Paraplegia due to a Homozygous ALS2 Exons 24–25 Deletion: Expanding the Genotypic Spectrum

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona, Maria Gnazzo, Silvia Genovese, Gessica Vasco, Lorena Travaglini, Maurizio Sabbadini, Marina Macchiaiolo, Francesco Nicita, Jacopo Sartorelli, Carmelo Piscopo, Enrico Castelli, Enrico Bertini, Andrea Bartuli, Antonio Novelli, Gessica Della Bella, Davide Vecchio   +15 more
wiley   +1 more source

The Adverse Effect of Spasticity on 3-Month Poststroke Outcome Using a Population-Based Model

Stroke Research and Treatment, 2014
Several devices and medications have been used to address poststroke spasticity. Yet, spasticity’s impact on outcomes remains controversial. Using data from a cohort of 460 ischemic stroke patients, we previously published a validated multivariable ...
S. R. Belagaje, C. Lindsell, C. J. Moomaw, K. Alwell, M. L. Flaherty, D. Woo, K. Dunning, P. Khatri, O. Adeoye, D. Kleindorfer, J. Broderick, B. Kissela   +11 more
doaj   +1 more source