Results 211 to 220 of about 147,177 (327)

Proteostasis of organelles in aging and disease

open access: yesThe FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi   +5 more
wiley   +1 more source

Central Nervous System Bleeding in Children With Haemophilia in Limited Resource

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Central nervous system (CNS) bleeding in children with haemophilia is a life‐threatening complication that may cause severe neurological sequelae or death. In resource‐limited settings, where prophylaxis is not universally accessible, its patterns and outcomes may differ from those in high‐income countries.
Patcharee Komvilaisak   +5 more
wiley   +1 more source

Aligning Minds in Spasticity Care-A Two-Phase Delphi-Dialogue Study of Patients and Professionals in Spain. [PDF]

open access: yesToxins (Basel)
Bascuñana-Ambrós H   +6 more
europepmc   +1 more source

An Australian standard of care for Niemann–Pick disease type C

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Niemann–Pick disease type C (NP‐C) is the fifth most prevalent lysosomal disorder in Australia. Diagnostic delay is common, impacted by disease heterogeneity, limited awareness within clinical gateway services and exclusion from state‐based newborn screening programmes.
Michel Tchan   +23 more
wiley   +1 more source

Spasticity may obscure motor learning ability after stroke.

open access: yesJournal of Neurophysiology, 2018
Sandeep K Subramanian   +2 more
semanticscholar   +1 more source

A Personal Exploration of Oral Health in Amyotrophic Lateral Sclerosis (ALS) Through the Eyes of a Multifaceted Authority

open access: yesJournal of Oral Rehabilitation, EarlyView.
This study resulted in agendas to improve oral health care, research, and education, advocating for a shift in ALS oral health care: from neglect to proactive integration. ABSTRACT Background and Objective Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that impairs motor function, including oral musculature, complicating
Merel C. Verhoeff   +2 more
wiley   +1 more source

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