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Treatment of spasticity

2023
Spasticity is characterized by an enhanced size and reduced threshold for activation of stretch reflexes and is associated with "positive signs" such as clonus and spasms, as well as "negative features" such as paresis and a loss of automatic postural responses.
Jonathan, Marsden   +2 more
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Spasticity management in the child with spastic quadriplegia

European Journal of Neurology, 2001
In children with spastic quadriplegia, also described as ‘whole body involvement’, spasticity can interfere with motor function, contributes to the development of deformities and adversely impacts on care, positioning, and comfort. In this population, spasticity interventions address goals such as improving comfort, reducing pain, easing the burden of ...
M E, Gormley, L E, Krach, L, Piccini
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Spastic Dysphonia

Annals of Otology, Rhinology & Laryngology, 1976
130 cases of spastic dysphonia are reviewed with special emphasis on the etiology of the disorder. An analysis of the circumstances surrounding the onset of the disease points strongly to a psychogenic origin of the disease in, at least, the vast majority of the cases.
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Management of Spasticity

American Journal of Physical Medicine & Rehabilitation, 1988
The functional impairment due to spasticity must be carefully assessed before any treatment is considered. Therapeutic intervention is best individualized to a particular patient. Basic principles of treatment to ameliorate spastic hypertonia are: 1) avoid noxious stimuli and 2) provide frequent range of motion.
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Tizanidine and spasticity

Neurology, 1995
There you go again: Th steadfast fad of fixing spasticity. To the Editor: Presentation of the problem. The Role of tizanidine in the treatment of spasticity, the recent 80-page supplement to Neurology [1] subsidized by the manufacturer of tizanidine, sets me up front [2] as the stalking horse entree of the symposium. Of course, I was flattered to gain
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Spastic ataxias

2018
The presence of spasticity and pyramidal features is a hallmark of some of hereditary ataxias, such as autosomal-recessive spastic ataxia of Charlevoix-Saguenay, other primary spastic ataxias, Friedreich ataxia, or ataxia with isolated vitamin E deficiency.
Olena, Bereznyakova, Nicolas, Dupré
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Quantification of Spasticity

Electroencephalography and Clinical Neurophysiology, 1983
Many different methods have been used to assess spasticity. They are all based on measurements of the responses to muscle stretch. The methods differ in how muscle stretch is obtained and how the responses are measured.
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Management of spasticity

Current Opinion in Neurology, 1997
Recent open studies and two placebo-controlled studies confirm the potential role of Botulinum toxin A in the treatment of focal spasticity in adults and children. The effect of the toxin might not only be mediated by the paresis of extrafusal, but also intrafusal muscle fibres, thereby altering the afferent discharge.
S, Hesse, K H, Mauritz
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SPASTIC PARAPLEGIA

Journal of the American Medical Association, 1934
Spastic paraplegia is a descriptive term and not a diagnosis. Its causes are many. In the classic form it is characterized by a progressive spasticity in the lower limbs, with all the signs and symptoms of a pyramidal tract disease below the level of the lesion. The onset is described by the patient in terms of fatigability of the lower limbs.
N. W. Winkelman, John L. Eckel
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Neurosurgery for Spasticity

Stereotactic and Functional Neurosurgery, 2000
Spasticity is usually a useful substitute for deficiency of motor strength. However not infrequently, it may become harmful leading to an aggravation of motor disability. When excessive spasticity is not sufficiently controlled by physical therapy and pharmacological treatment, patients can have recourse to neurosurgery: neurostimulation, intrathecal ...
M P, Sindou, P, Mertens
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