Results 61 to 70 of about 166,105 (376)
Long-Term Care Resident Awareness and Interest in Spasticity Treatments
Geriatrics, 2021 Spasticity is common in long-term care settings (affecting up to one in three residents), yet it remains under-treated despite safe and effective, Food and Drug Administration (FDA)-approved therapies. One barrier to treatment may be lack of awareness of
Mallory L. Hacker +7 more
doaj +1 more source
NeuroRehabilitation (Reading, MA), 2019 BACKGROUND: The upper extremity spasticity following stroke limits individuals’ activities of daily living. Focal muscle vibration (FMV) is a device producing vibration signals affecting the central nervous system.
A. Alashram +3 more
semanticscholar +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Toxins, 2021 Spastic equinovarus (SEV) foot deformity is commonly observed in patients with post-stroke spasticity. Tibialis posterior (TP) is a common target for botulinum toxin type-A (BoNT-A) injection, as a first-line treatment in non-fixed SEV deformity.
Stefania Spina +9 more
doaj +1 more source
Impaired H-Reflex Adaptations Following Slope Walking in Individuals With Post-stroke Hemiparesis [PDF]
, 2019 Background and Purpose: Short term adaptations in the Ia afferent-motoneuron pathway, as measured using the H-reflex, in response to altered ground reaction forces (GRFs) applied at the feet during slope walking have been observed in the non-impaired ...
Akoopie, Eric +5 more
core +2 more sources
Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects
Annals of Neurology, 2018 To identify novel causes of recessive ataxias, including spinocerebellar ataxia with saccadic intrusions, spastic ataxias, and spastic paraplegia.
E. Seong +18 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake +12 more
wiley +1 more source
Cryoneurolysis of the Femoral Nerve for Focal Spasticity in an Ambulatory Patient
Archives of Rehabilitation Research and Clinical TranslationIntroduction: Spasticity of the knee extensors is a common presentation among patients with multiple sclerosis. The resulting stiff leg gait can result in increased risk of falls, heightened energy expenditure during gait, lowered gait speed, and ...
Ève Boissonnault, MD +4 more
doaj +1 more source
Journal of Rehabilitation Medicine, 2017 Oral baclofen has long been a mainstay in the management of spasticity. This review looks at the clinical evidence for the efficacy and safety of oral baclofen in patients with spasticity of any origin or severity, to determine whether there is a ...
P. Ertzgaard, C. Campo, A. Calabrese
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source