Results 61 to 70 of about 56,757 (311)
Frontiers in Bioengineering and Biotechnology, 2022 Background: Despite recent developments in the methodology for measuring spasticity, the discriminative capacity of clinically diagnosed spasticity has not been well established.
Hiroki Tanikawa +10 more
doaj +1 more source
Management of spasticity [PDF]
Age and Ageing, 1998 Spasticity is a major challenge to the rehabilitationteam. Spasticity can prevent or hamper function, causepain, disturb sleep, cause unnecessary complicationsand present major difficulties for care workers. Thisarticle reviews the variety of options available for theclinical management of spasticity.
openaire +2 more sources
Spasticity Mechanisms – for the Clinician [PDF]
Frontiers in Neurology, 2010 Spasticity, a classical clinical manifestation of an upper motor neuron lesion, has been traditionally and physiologically defined as a velocity dependent increase in muscle tone caused by the increased excitability of the muscle stretch reflex.
Mukherjee, Angshuman, Chakravarty, Ambar
openaire +3 more sources
Fabric‐Based Wearable Robotic Exoskeleton Gloves: Advancements and Challenges
Advanced Materials Technologies, EarlyView.This review highlights interdisciplinary technological advances in fabric‐based robotic gloves, focusing on progress in design, fabrication, actuation, sensing, control, and power and energy requirements. It also addresses performance testing and validation, including biomechanical, strength, functional, user experience, and durability assessments, to ...
Ayse Feyza Yilmaz +2 more
wiley +1 more source
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Stroke Research and Treatment, 2014 Background. Arm spasticity is a challenge in the care of chronic stroke survivors with motor deficits. In order to advance spasticity treatments, a better understanding of the mechanism of spasticity-related neuroplasticity is needed. Objective.
Svetlana Pundik +4 more
doaj +1 more source
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Advanced Science, EarlyView.This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang +14 more
wiley +1 more source
Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier +2 more
wiley +1 more source