Results 21 to 30 of about 2,266,463 (249)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Spatial ability, urban wayfinding and location-based services:a review and first results [PDF]
Location-Based Services (LBS) are a new industry at the core of which are GISand spatial databases. With increasing mobility of individuals, the anticipatedavailability of broadband communications for mobile devices and growingvolumes of location ...
Li, C
core
Spectral pre-modulation of training examples enhances the spatial resolution of the Phase Extraction Neural Network (PhENN) [PDF]
The Phase Extraction Neural Network (PhENN) is a computational architecture, based on deep machine learning, for lens-less quantitative phase retrieval from raw intensity data.
Barbastathis, George, Li, Shuai
core +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A novel internal waves generator [PDF]
We present a new kind of generator of internal waves which has been designed for three purposes. First, the oscillating boundary conditions force the fluid particles to travel in the preferred direction of the wave ray, hence reducing the mixing due to ...
Dauxois, Thierry +3 more
core +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The gap between our ability to collect interesting data and our ability to analyze these data is growing at an unprecedented rate. Recent algorithmic attempts to fill this gap have employed unsupervised tools to discover structure in data.
Flaspohler, Genevieve +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Generalized Spatial Measure for Resilience of Microbial Systems [PDF]
The emergent property of resilience is the ability of a system to return to an original state after a disturbance. Resilience may be used as an early warning system for significant or irreversible community transition; that is, a community with ...
Lindemann, Stephen R. +2 more
core +3 more sources

