Results 101 to 110 of about 453,054 (303)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
A spatial analysis of residential land prices in Belgium : accessibility, linguistic border and environmental amenities [PDF]
This paper explores the spatial variation of land prices in Belgium. The originality of the methodology is threefold : (1) to work at the spatial extent of an entire country, (2) to compute several accessibility measures to all jobs and several ...
Florence Goffette-Nagot +2 more
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Aggregate and Regional Economic Effects of New Railway Infrastructure [PDF]
Economists expect positive returns to investments in infrastructure. However a project with higher national returns might have less favorable effects on a regional level than the alternative.
Richard Sellner +2 more
core +4 more sources
IEEE Access, 2018 The spatial accessibility to urban health services is a key issue for urban environment and public health studies, especially among developing countries with explosive population growth and limited urban land space.
Wenhao Yu +4 more
doaj +1 more source
Secure Spatial Multiple Access Using Directional Modulation
IEEE Transactions on Wireless Communications, 2018 In this paper, we introduce a secure multiple access scheme, which exploits the multipath structure of the channel to create a multi-user interference environment. The generated interference enables legitimate users to share time and frequency resources over spatially secure communication links.
Mohammed Hafez +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
On Space-Time Changes of Hedonic Prices for Single Family Homes [PDF]
The level of and changes in prices for homes reflect the space-time dynamics in valuation of the underlying attributes connected with the objects. In this paper hedonic prices for single family homes distributed over two Swedish counties are estimated ...
Krister Sandberg
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