Results 81 to 90 of about 2,789,688 (309)
Development and Application of an Activity Based Space-Time Accessibility Measure for Individual Activity Schedules [PDF]
Accessibility is an important aspect of human existence impacting on our notion of society equity and justice. It plays an important role in a number of existing theories of spatial and travel behaviour in addition to affecting the rate and the pattern ...
Olu Ashiru, John Polak, Robert B. Noland
core
Accessibility Monitor 2011 of Municipalities
, 2013 Onderzoek naar de kwaliteit en toegankelijkheid van de websites van alle Nederlandse gemeenten en van de website van de Rijksoverheid. Vanaf 10 mei 2013 zijn de bijbehorende data beschikbaar, zie het veld 'Date available'
Stichting Accessibility
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Smart CitiesThis article presents a modular and replicable framework to assess spatial accessibility to essential public services in the Lazio Region (Italy). Current policies, framed within the EU Urban Agenda and the UN Sustainable Development Goals, emphasize ...
Kevin Gumina +3 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Open GeosciencesEvaluating and optimizing the accessibility of public facilities is a crucial task in urban planning and resource allocation. However, existing studies seldom consider the impact of human activity intensity on spatial accessibility, which leads to the ...
Bai Jielian +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Statistical Analysis of the Relationship between Public Transport Accessibility and Flat Prices in Riga [PDF]
A relationship between public transport accessibility and residential land value is a point of interest of many recent researches. A hedonic price regression model, widely used in this research area, has one very important shortcoming – it calculates an "
Pavlyuk, Dmitry
core
Choice and the composition of general practice patient registers [PDF]
, 2009 Choice of general practice (GP) in the National Health Service (NHS), the UKs universal healthcare service, is a core element in the current trajectory of NHS policy. This paper uses an accessibility-based approach to investigate the pattern of patient
Longley, P., Lewis, D., Mateos, P.
core
Holistic approaches to e‐learning accessibility [PDF]
, 2006 The importance of accessibility to digital e‐learning resources is widely acknowledged. The World Wide Web Consortium Web Accessibility Initiative has played a leading role in promoting the importance of accessibility and developing guidelines that can ...
Kelly, Brian +5 more
core +1 more source