Results 101 to 110 of about 2,789,688 (309)

External development potential of brownfield sites in the Czech–Polish cross-border post-industrial region: A network-based assessment

Moravian Geographical Reports
Brownfield transformation is not only a technical and environmental task, but increasingly a cross-scalar governance challenge, particularly in European cross-border regions where planning systems, legislation and development trajectories intersect.
Bárta Martin, Krtička Luděk, Dvořák Petr, Hamerla Adam, Spyra Marcin   +4 more
doaj   +1 more source

Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers

eLife
As the genome is organized into a three-dimensional structure in intracellular space, epigenomic information also has a complex spatial arrangement. However, most epigenetic studies describe locations of methylation marks, chromatin accessibility regions,
Yeming Xie, Fengying Ruan, Yaning Li, Meng Luo, Chen Zhang, Zhichao Chen, Zhe Xie, Zhe Weng, Weitian Chen, Wenfang Chen, Yitong Fang, Yuxin Sun, Mei Guo, Juan Wang, Shouping Xu, Hongqi Wang, Chong Tang   +16 more
doaj   +1 more source

Assessing Spatial Accessibility of Public and Private Residential Aged Care Facilities: A Case Study in Wuhan, Central China

ISPRS International Journal of Geo-Information, 2017
In the increasingly serious aging China, aged service is the provision of one of the most urgent and important public services to citizens, and private facilities has become an important service force with the aged service market opening in China.
Enxiang Cai, Yaolin Liu, Ying Jing, Lei Zhang, Jiwei Li, Chaohui Yin   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Potential accessibility - an interesting conceptual framework to address strategic planning issues in the Amsterdam region? [PDF]

It is difficult to prove a direct causal link between the spatial patterns of economic activities and the quality of the transport system. But it seems obvious that the transport system creates conditions, which enable economic activities to interact ...
Thomas Straatemeier
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Beyond spatial accessibility. Redefining access to services through digital connectivity [PDF]

Ensuring equal opportunities for access to goods and services represents a key objective of sustainable development policies, in line with the principle of "Accessibility for all".
Paddeu, Daniela, Balletto, Ginevra, Ladu, Mara, Corona, Laura   +3 more
core  

Spatial Accessibility in the Urban Environment of a Medium-Sized City: A Case Study of Public Amenities in Odense, Denmark

Urban Science
Spatial accessibility is a key principle in urban studies, shaping how people reach amenities and services across cities. While most research concentrates on large metropolitan areas and central urban services, small and medium-sized cities and their ...
Irma Kveladze
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source