Results 131 to 140 of about 137,716 (306)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Relationships between ramp metering and sprawl [PDF]
This paper explores impacts of ramp metering on urban land use. A regression-based transportation model is developed to capture changes in accessibility caused by ramp metering on a highway network. A Land Use Change Indicator (LUCI) model is modified to
Lei Zhang, David Levinson
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
A relationship between public transport accessibility and residential land value is a point of interest of many recent researches. A hedonic price regression model, widely used in this research area, has one very important shortcoming – it calculates an "
Pavlyuk, Dmitry
core +1 more source
Place Rank: Valuing Spatial Interactions [PDF]
Accessibility measures the potential of opportunities for interaction. This paper proposes and explores a new flow-based measure, 'place rank' using origin-destination information.
Ahmed El-Geneidy, David Levinson
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Spatial-Temporal dynamics of surface water flooding and consequences for emergency services accessibility [Abstract] [PDF]
, 2016 Spatial-Temporal dynamics of surface water flooding and consequences for emergency services accessibility ...
Lili Yang (1252140) +6 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Choice and the composition of general practice patient registers
, 2009 Choice of general practice (GP) in the National Health Service (NHS), the UKs universal healthcare service, is a core element in the current trajectory of NHS policy. This paper uses an accessibility-based approach to investigate the pattern of patient
Longley, P., Lewis, D., Mateos, P.
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
High-speed rail’s impact on the location of office employment within the Dutch Randstad area [PDF]
With the upcoming implementation of high-speed railway infrastructure in the Netherlands, interest has arisen in the spatial-economic effects this might have.
Bert Van Wee +2 more
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