Results 151 to 160 of about 2,789,688 (309)
Traffic Accessibility and the Effect on Firms and Population in 99 Austrian Regions [PDF]
In this paper we describe the EAR (regional economic accessibility) model to investigate the impact of the improvement of railroad infrastructure on regional GDP, population and firms growth in 99 Austrian regions.
Polasek, Wolfgang +1 more
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Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
A Theoretical Model for Measuring the Influence of Accessibility in Residential Choice Behaviour [PDF]
Due to the renewed interest for Integrated Land-use and Transport models, the urge for sound models that describe the behaviour of the agents on the urban markets has grown.
Berry Blijie
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Accessibility of spatial channels
Journal of Vision, 2010 R. F. Hess, Y.-Z. Wang, C. H. Liu
openaire +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Unemployment duration, city size, and the tightness of the labor market [PDF]
This paper attempts to determine whether residential location affects unemployment duration. Our analysis is based on a spatial job search framework that shows the importance of dissociating the role of travel time from physical distance in unemployment ...
Carl Gaigné, Cécile Détang-Dessendre
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Network geography: relations, interactions, scaling and spatial processes in GIS [PDF]
, 2003 This chapter argues that the representational basis of GIS largely avoidseven the most rudimentary distortions of Euclidean space as reflected, forexample, in the notion of the network. Processes acting on networks whichinvolve both short and longer term
Batty, M
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
International accessibility and rental levels: a case study for the office-market in the Netherlands [PDF]
Rental levels of office floor space are determined by aspects of the buildings and aspects of the location. In this contribution we focus on the characteristics of locations using a large database of market-transactions.
Gordijn, Hugo, de Bok, Michiel Adriaan
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