Results 41 to 50 of about 2,789,688 (309)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Novel methods for the estimation of cost–distance decay in potential accessibility models
, 2014 In much accessibility research, arbitrary estimates of the distance sensitivity parameters have been used to represent the distance decay parameters in potential accessibility models.
Östh, John, +2 more
core +1 more source
A Random Multiple-Access Protocol with Spatial Interactions [PDF]
Journal of Applied Probability, 2007 We analyse an ALOHA-type random multiple-access protocol where users have local interactions. We show that the fluid model of the system workload satisfies a certain differential equation. We obtain a sufficient condition for the stability of this differential equation and deduce from that a sufficient condition for the stability of the protocol.
Charles Bordenave +2 more
openaire +7 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Effective Data Management and Spatial Analytics
, 2021 This webinar introduced the implementations of effective data management and spatial analytics by academic and industry leaders of the field, and discuss the directions for further enhancement through integration with a cloud-based platform for research ...
Spatial Data Lab
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Measuring accessibility to health care services for older bus passengers: A finer spatial resolution [PDF]
, 2021 Health care accessibility is a vital indicator for evaluating areas where there are medical shortages. However, due to the lack of population data with a satisfactory spatial resolution, efforts to accurately measure health care accessibility among older
Cheng, L. +4 more
core +1 more source
The accessibility of spatial channels for stereo and motion
Vision Research, 2006 Using fractal noise images, we measured the dependence of D(min) on the spatial passband (spatial frequency and orientation) over which information was correlated either between the eyes for stereo or between sequential frames for motion. Without affecting the amplitude spectrum of the noise stimulus we used idealized filters to scramble the phase of ...
Hess, Robert F. +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source