Results 91 to 100 of about 1,688,232 (308)

A balanced view of scale in spatial statistical analysis [PDF]

, 2002
Concepts of spatial scale, such as extent, grain, resolution, range, footprint, support and cartographic ratio are not interchangeable. Because of the potential confusion among the definitions of these terms, we suggest that authors avoid the term "scale"
Jakomulska, A., J. L. Dungan, Dungan, J. L., M. R. T. Dale, J. N. Perry, Perry, J. N., Citron-Pousty, S., P. Legendre, Fortin, M-J., M.‐J. Fortin, Legendre, P., M. Miriti, Rosenberg, M. S., S. Citron‐Pousty, Miriti, M., A. Jakomulska, M. S. Rosenberg, Dale, M. R. T.   +17 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Spatial Econometric data analysis: moving beyond traditional models [PDF]

, 2003
This article appraises recent advances in the spatial econometric literature. It serves as the introduction too collection of new papers on spatial econometric data analysis brought together in this special issue, dealing specifically with new extensions
van der Vlist, A.J., Florax, R.J.G.M.
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Evaluating Spatial Design Techniques for Solving Land-use Allocation Problems [PDF]

, 2005
This study examines the use of spatial optimization techniques for multi-site land-use allocation problems (MLUA). 'Multi-site' refers to the problem of allocating more than one land-use type in an area, which are difficult problems as they involve ...
Herwijnen, M. van, Van Herwijnen, Marjan, Theodor Stewart, Aerts, Jeroen C J H, Janssen, Ron, Stewart, Theodor J., Marjan Van Herwijnen, Ron Janssen, Janssen, R.; id_orcid, Aerts, J.C.J.H., Janssen, R., Jeroen Aerts, van Herwijnen, M., Stewart, T.J.   +13 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Spatial analysis of BSE cases in the Netherlands [PDF]

, 2008
Background In many of the European countries affected by Bovine Spongiform Encephalopathy (BSE), case clustering patterns have been observed. Most of these patterns have been interpreted in terms of heterogeneities in exposure of cattle to the BSE agent.
Thomas J Hagenaars, Heres Lourens, Dick J Brus, Brus Dick J, Brus, D.J., Hagenaars, T.H.J., Heres, L., Lourens Heres, Hagenaars Thomas J   +8 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source