Results 101 to 110 of about 4,349,499 (279)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Machine learning algorithms of riverbed change and environments of the Lower Apalachicola River

open access: yesDiscover Applied Sciences
Coastal areas, deltas, and the lower end of large rivers have experienced profound long-term changes, destabilizing the environmental balance over the previous several decades.
Ali R. Alruzuq, Joann Mossa
doaj   +1 more source

Reconstructing Snow-Free Sentinel-2 Satellite Imagery: A Generative Adversarial Network (GAN) Approach

open access: yesRemote Sensing
Sentinel-2 satellites are one of the major instruments in remote sensing (RS) technology that has revolutionized Earth observation research, as its main goal is to offer high-resolution satellite data for dynamic monitoring of Earth’s surface and climate
Temitope Seun Oluwadare   +5 more
doaj   +1 more source

A Spatial Econometric Analysis of Regional Specialisation Patterns Across EU Regions [PDF]

open access: yes
This paper conducts a spatial econometric analysis of the determinants of regional specialisation patterns. Spatial autocorrelation is present, but is mostly due to spatial error autocorrelation.
Stirböck, Claudia
core  

Modelling as a tool for spatial planning of commodity production: the example of certified oil palm plantations in Central Africa [PDF]

open access: yes, 2014
The Central African region is targeted by agri-business companies as a suitable place to develop large plantations. Most of the existing assessments of available land are based on an a priori definition of availability and without any operational-level ...
Feintrenie, Laurène   +3 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

STEPNet: A Spatial and Temporal Encoding Pipeline to Handle Temporal Heterogeneity in Climate Modeling Using AI: A Use Case of Sea Ice Forecasting

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sea ice forecasting remains a challenging topic due to the complexity of understanding its driving forces and modeling its dynamics. This article contributes to the expanding literature by developing a data-driven, artificial intelligence (AI)-based ...
Sizhe Wang, Wenwen Li, Chia-Yu Hsu
doaj   +1 more source

Spatial Mixing of Coloring Random Graphs

open access: yes, 2014
We study the strong spatial mixing (decay of correlation) property of proper $q$-colorings of random graph $G(n, d/n)$ with a fixed $d$. The strong spatial mixing of coloring and related models have been extensively studied on graphs with bounded maximum
A. Frieze   +8 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

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