Life in the desert: habitat spatial complexity, gene flow, and functional connectivity in Ivesia webberi [PDF]
Israel Borokini +2 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Low-Complexity Detection Algorithms for Spatial Modulation MIMO Systems
In this paper, the authors propose three low-complexity detection schemes for spatial modulation (SM) systems based on the modified beam search (MBS) detection.
Xinhe Zhang +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Low-complexity optimal MPSK detection for spatial modulation
The low-complexity optimal SM detection algorithm for MQAM signal detection had been proposed,but no similar method was found for MPSK signal.The problem of low-complexity detection for MPSK signal was considered in SM systems.Utilizing 2-D vector ...
Hong-zhi MEN, Ming-lu JIN
doaj +2 more sources
Spatial Complexity of a Predator-Prey Model with Holling-Type Response
We focus on a spatially extended Holling-type IV predator-prey model that contains some important factors, such as noise (random fluctuations), external periodic forcing, and diffusion processes.
Lei Zhang, Zhibin Li
doaj +1 more source
Modelling H5N1 in Bangladesh across spatial scales: Model complexity and zoonotic transmission risk
Highly pathogenic avian influenza H5N1 remains a persistent public health threat, capable of causing infection in humans with a high mortality rate while simultaneously negatively impacting the livestock industry.
Edward M. Hill +9 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

