Results 91 to 100 of about 1,009,749 (294)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Shaping the waveform of entangled photons
, 2007 We demonstrate experimentally the tunable control of the joint spectrum, i.e. waveform and degree of frequency correlations, of paired photons generated in spontaneous parametric downconversion.
A. B. U’Ren +7 more
core +1 more source
Visualizing GPR Data Using Spatial-Subband Configuration
IEEE Access, 2018 In ground penetrating radar (GPR) applications, base-scale analysis can be a powerful tool to support data analysis and to build a consensus in data interpretation.
Da Yuan, Mei Hong, Zhiyong An
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Readout and performance of thick CZT strip detectors with orthogonal coplanar anodes [PDF]
, 2002 We report progress in the study of CZT strip detectors featuring orthogonal coplanar anode contacts. The work includes laboratory and simulation studies aimed at optimizing and developing compact, efficient, high performance detector modules for 0.05 to ...
Donmez, B +8 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A comparative study of the spatial pattern in rural settlements; The case study of Shalheh-ye Emam Hasan of Abadan and Hadbeh khanafereh of Shadegan [PDF]
مسکن و محیط روستا, 2020 The village is a long-standing form of human settlement that embodies the vernacular pattern of human habitation and innovative ways of adapting to the environment.
Mohamad Ebrahim Mazhari +2 more
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Design and Value: Spatial Form and the Economic Failure of a Mall [PDF]
Real estate analysts have not had the tools to identify the functional problems of real estate because they have not focused on configuration. Space syntax is a way to represent, describe and evaluate spatial configurations or patterns created through ...
M. Gordon Brown
core