Results 91 to 100 of about 202,726 (265)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Configuration dependence of scotopic spatial summation
The Journal of Physiology, 1971 1. Psychophysical experiments were done under conditions of complete dark adaptation, 7° in the human temporal retina, using blue‐green flashes brief enough to be within the range of complete temporal summation.2. Frequency‐of‐seeing experiments were done for two 3·4′ squares separated by 20′ or 23′ and for each square separately.
openaire +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The spatial configuration of local climate zones reveals effects on wayfinding in human walking. [PDF]
PLoS One, 2023 Fan PY +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Geoprocessamento e a promoção da saúde: desigualdades sociais e ambientais em São Paulo
Revista de Saúde PúblicaOBJETIVO: Caracterizar as desigualdades sociais, que se configuram em condições de risco aos agravos respiratórios em crianças e descrever os usos de técnicas de geoprocessamento na identificação de grupos sociais homogêneos e as ações de intervenção no ...
Anna Maria Chiesa +2 more
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Analysis of the Spatial Configuration in Cinema on a Human Scale: ‘The Secret World of Arrietty’
EtkileşimSpace design is a research field with a broad framework that interacts with different disciplines. Scale, one of the most important components of this field, is used to increase the cinematic effect in the configuration of f ilm spaces.
Zeynep Fatma Niğdeli +1 more
doaj +1 more source
Editorial: Chromatin Spatial Configuration and Function in Metazoans. [PDF]
Front Genet, 2021 Delgado-Olguín P +2 more
europepmc +1 more source