Results 51 to 60 of about 933,538 (267)
The gender dimensions of travel time use in Germany
European Transport Research Review, 2023 Highlights Men’s solitary ICT use during travel is driven by their economic situation and preference for ICT use. Women’s socializing during travel is primarily influenced by their children and preference for ICT use.
Bhuvanachithra Chidambaram +1 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Spatial planning practices of adapting to climate change
European Journal of Spatial Development, 2015 Although spatial planning is considered as crucial for climate change adaption, e.g. in the EU White Paper on Adaptation, there are uncertainties regarding the role of adaptation strategies in spatial planning practices. In this paper the potential role
Bart Jan Davidse +2 more
doaj +3 more sources
LandTourism has become a structural driver of land-system transformation, influencing urban restructuring, rural land consumption, coastal development, and housing dynamics.
Dimitris Kourkouridis +4 more
doaj +1 more source
Development of the discrimination of spatial phase in infancy
Vision Research, 1986 The ability to discriminate grating patterns, containing the same spatial frequency components but in different phase relationships, has been studied in infants by comparing looking times following habituation to one pattern. The performance of 1-month-olds was compared with that of 2/3-month-old infants.
Braddick, O +2 more
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
SensorsA low-cost, tri-axial 50 Hz magnetic field monitoring sensor was designed, calibrated and verified. The sensor was designed using off-the-shelf components and commercially available coils.
Kenneth Deprez +9 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source