Results 61 to 70 of about 879,955 (267)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Mediterranean region, identified by scientists as a ‘climate hot spot’, is experiencing warmer and drier conditions, along with an increase in the intensity and frequency of extreme weather events. One such extreme phenomena is droughts.
Aikaterini Stamou +6 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
High-resolution remotely sensed data, which are characterised by their advanced spectral and spatial capabilities, provide unprecedented opportunities to monitor and analyse the dynamic structures of urban environments. Platforms like Google Earth Engine
Aikaterini Stamou +6 more
doaj +1 more source
The role of seismic simulators in earthquake engineering and public perception of structural safety [PDF]
Constructions located in various environmental conditions represent physical components of human habitat and earthquakes are often a cause of sudden damage and urban or rural destructuring.
Vasile MEIŢĂ +3 more
doaj
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Experimental research and laboratory tests for seismic qualification of an “Automatica - PL2023” junction box [PDF]
The paper deals with some aspects regarding "Experimental Research and Laboratory Testing for Seismic Qualification DBE B, Seismic Edge HCLPF = 0.4g, Automatica 1 (2) - 52900 - PL2023 Junction Box".
Florin-Radu HARIGA +2 more
doaj
Fire resistance testing of ETICS systems in Romania [PDF]
The fire security of buildings can be increased by the decrease of fire propagation intensity resulting from compartment fires and by using sustainable building enveloping solutions, with the role of limiting the spread of fires to neighboring floors and
Adrian SIMION +3 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

