Results 61 to 70 of about 879,955 (267)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Mapping Drought Incidents in the Mediterranean Region with Remote Sensing: A Step Toward Climate Adaptation

open access: yesLand
The Mediterranean region, identified by scientists as a ‘climate hot spot’, is experiencing warmer and drier conditions, along with an increase in the intensity and frequency of extreme weather events. One such extreme phenomena is droughts.
Aikaterini Stamou   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Satellite Imagery for Comprehensive Urban Morphology and Surface Roughness Analysis: Leveraging GIS Tools and Google Earth Engine for Sustainable Urban Planning

open access: yesUrban Science
High-resolution remotely sensed data, which are characterised by their advanced spectral and spatial capabilities, provide unprecedented opportunities to monitor and analyse the dynamic structures of urban environments. Platforms like Google Earth Engine
Aikaterini Stamou   +6 more
doaj   +1 more source

The role of seismic simulators in earthquake engineering and public perception of structural safety [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2017
Constructions located in various environmental conditions represent physical components of human habitat and earthquakes are often a cause of sudden damage and urban or rural destructuring.
Vasile MEIŢĂ   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Experimental research and laboratory tests for seismic qualification of an “Automatica - PL2023” junction box [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2017
The paper deals with some aspects regarding "Experimental Research and Laboratory Testing for Seismic Qualification DBE B, Seismic Edge HCLPF = 0.4g, Automatica 1 (2) - 52900 - PL2023 Junction Box".
Florin-Radu HARIGA   +2 more
doaj  

Fire resistance testing of ETICS systems in Romania [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2021
The fire security of buildings can be increased by the decrease of fire propagation intensity resulting from compartment fires and by using sustainable building enveloping solutions, with the role of limiting the spread of fires to neighboring floors and
Adrian SIMION   +3 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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