Results 41 to 50 of about 374,822 (264)

Effect of chronic administration of arachidonic acid on the performance of learning and memory in aged rats

open access: yesFood & Nutrition Research, 2019
Background: Arachidonic acid (AA, C20:4, ω-6) is a ω-6 polyunsaturated fatty acid (PUFA) and plays diverse roles in cell signaling. Numerous reports on the effects of ω-3 PUFAs, such as docosahexaenoic acid (DHA, C22:6, ω-3) and eicosapentaenoic acid ...
Takayuki Inoue   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Environmental Enrichment Improved Learning and Memory, Increased Telencephalic Cell Proliferation, and Induced Differential Gene Expression in Colossoma macropomum

open access: yesFrontiers in Pharmacology, 2020
Fish use spatial cognition based on allocentric cues to navigate, but little is known about how environmental enrichment (EE) affects learning and memory in correlation with hematological changes or gene expression in the fish brain. Here we investigated
Patrick Douglas Corrêa Pereira   +20 more
doaj   +1 more source

From Topological Analyses to Functional Modeling: The Case of Hippocampus

open access: yesFrontiers in Computational Neuroscience, 2021
Topological data analyses are widely used for describing and conceptualizing large volumes of neurobiological data, e.g., for quantifying spiking outputs of large neuronal ensembles and thus understanding the functions of the corresponding networks ...
Yuri Dabaghian
doaj   +1 more source

Learning spatial relations in object recognition [PDF]

open access: yesPattern Recognition Letters, 2006
This paper studies two types of spatial relationships that can be learned from training examples for object recognition. The first one employs deformable relationships between object parts with a Gaussian model, while the second one describes pairwise relationships between pixel intensity values using Bayesian networks.
T.V. Pham, A.W.M. Smeulders (Arnold)
openaire   +3 more sources

The effect of load on spatial statistical learning

open access: yesScientific Reports, 2023
AbstractStatistical learning (SL), the extraction of regularities embedded in the environment, is often viewed as a fundamental and effortless process. However, whether spatial SL requires resources, or it can operate in parallel to other demands, is still not clear.
Nadav Amsalem, Tomer Sahar, Tal Makovski
openaire   +3 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Allocentric Spatial Memory Performance in a Virtual Reality-Based Task is Conditioned by Visuospatial Working Memory Capacity

open access: yesBrain Sciences, 2020
Traditionally, the medial temporal lobe has been considered a key brain region for spatial memory. Nevertheless, executive functions, such as working memory, also play an important role in complex behaviors, such as spatial navigation.
Joaquín Castillo Escamilla   +5 more
doaj   +1 more source

Covert Reorganization / Spatial Learning [PDF]

open access: yes, 2012
info:eu-repo/semantics ...
Rauchs, Géraldine, Peigneux, Philippe
openaire   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

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