Results 51 to 60 of about 8,739,015 (304)

Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice

open access: yesLife, 2022
Using an in vivo method for the assessment of polyphosphoinositide (PI) hydrolysis, we examine whether spatial learning and memory extinction cause changes in mGlu5 metabotropic glutamate receptor signaling in the hippocampus and prefrontal cortex.
Ana Elena Teleuca   +10 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Influence of Project-Based Learning (PJBL) Model on Spatial Thinking Ability in Class SMA PGRI 2 Palembang

open access: yes, 2019
One of the goals of learning geography is to give students the ability to think spatially. But based on observations in the field, it shows that students' spatial thinking skills have not shown maximum results.

core   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

open access: yesAdvanced Science
Rhythmic light flicker alleviates cognitive impairments in various animal models of neurological diseases. However, its long‐term effects and underlying mechanisms remain unclear.
Hai Yan   +16 more
doaj   +1 more source

Learning spatial relations in object recognition [PDF]

open access: yesPattern Recognition Letters, 2006
This paper studies two types of spatial relationships that can be learned from training examples for object recognition. The first one employs deformable relationships between object parts with a Gaussian model, while the second one describes pairwise relationships between pixel intensity values using Bayesian networks.
T.V. Pham, A.W.M. Smeulders (Arnold)
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The effect of load on spatial statistical learning

open access: yesScientific Reports, 2023
AbstractStatistical learning (SL), the extraction of regularities embedded in the environment, is often viewed as a fundamental and effortless process. However, whether spatial SL requires resources, or it can operate in parallel to other demands, is still not clear.
Nadav Amsalem, Tomer Sahar, Tal Makovski
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Work Integrated Learning: Will it Work for Spatial Science Wilers? [PDF]

open access: yes, 2008
University courses often describe an intention to produce graduate students who are work ready and who have had ‘hands-on’ industry experience. Work Integrated Learning programmes (in various forms) in university courses are not new.
Webb, Robert M., Hayes, John F.
core   +1 more source

Cognitive and cartographic representations: towards a comprehensive approach

open access: yesCybergeo, 2002
In order to clearly understand the cognitive representations of the urban space, this paper presents an approach in three steps: identification, which highlights the importance of a place; its location more or less exact which indicates the level of the ...
Colette Cauvin
doaj   +1 more source

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