Results 41 to 50 of about 25,082 (249)

Multi-Bessel Beams Generated by an Axicon and a Spatial Light Modulator for Drilling Applications

open access: yesPhotonics, 2023
We report on an optical setup to generate multi-Bessel beam profiles combining a refractive axicon and a spatial light modulator. Based on their particular beam profile, Bessel beams offer advantageous properties for micro drilling processes and internal
Christian Lutz   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Parallel femtosecond laser processing with vector-wave control

open access: yesMATEC Web of Conferences, 2013
Parallel femtosecond laser processing with a computer-generated hologram displayed on a spatial light modulator, has the advantages of high throughput and high energy-use efficiency.
Hayasaki Yoshio, Hasegawa Satoshi
doaj   +1 more source

Adjustable Optical Slit Based on the Phase Type Spatial Light Modulator

open access: yesIEEE Photonics Journal, 2019
In this paper, we propose an adjustable optical slit based on a phase type spatial light modulator (SLM). The adjustable optical slit consists of two polarized beam splitters and one SLM. The SLM is used to modulate the phase of light.
Di Wang, Chao Liu, Qiong-Hua Wang
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

UV Durable LCOS for Laser Processing

open access: yesCrystals, 2021
Liquid-Crystal-On-Silicon (LCOS) Spatial Light Modulator (SLM) is widely used as a programmable adaptive optical element in many laser processing applications with various wavelength light sources.
Yasuki Sakurai   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Ghost imaging object recognition based on self-attention mechanism network

open access: yesAIP Advances, 2023
A network model based on the self-attention mechanism is proposed to address the difficulties in extracting features from ghost imaging targets, low recognition efficiency, and potential errors.
Yunting He, Sheng Yuan, Jiali Song
doaj   +1 more source

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