Results 71 to 80 of about 21,167 (259)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Comparative simulations of Fresnel holography methods for atomic waveguides

New Journal of Physics, 2016
We have simulated the optical properties of micro-fabricated Fresnel zone plates (FZPs) as an alternative to spatial light modulators for producing non-trivial light potentials to trap atoms within a lensless Fresnel arrangement.
V A Henderson, P F Griffin, E Riis, A S Arnold   +3 more
doaj   +1 more source

Pulse Burst Generation and Diffraction with Spatial Light Modulators for Dynamic Ultrafast Laser Materials Processing. [PDF]

Materials (Basel), 2022
Fang Z, Zhou T, Perrie W, Bilton M, Schille J, Löschner U, Edwardson S, Dearden G.   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Lithium niobate thin film electro-optic modulator

Nanophotonics
The linear electro-optic effect offers a valuable means to control light properties via an external electric field. Lithium niobate (LN), with its high electro-optic coefficients and broad optical transparency ranges, stands out as a prominent material ...
Liu Jikun, Qu Lun, Wu Wei, Jin Chunyan, Chen Zhihao, Gu Zhidong, Liu Weiye, Wang Chenxiong, Zheng Dahuai, Liu Hongde, Cai Wei, Ren Mengxin, Xu Jingjun   +12 more
doaj   +1 more source

Nonsequential Speckle Reduction Method by Generating Uncorrelated Laser Subbeams With Equivalent Intensity Using a Reflective Spatial Light Modulator

IEEE Photonics Journal, 2017
Sequential speckle reduction methods demand the usage of fast modulators due to the short integration period of human eyes. Here, a nonsequential speckle reduction method by splitting one laser beam with short coherence length into uncorrelated laser ...
Zhaomin Tong, Shaohua Song, Suotang Jia, Xuyuan Chen   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Universal phase-only spatial light modulators

Optics Express, 2017
Universal phase-only spatial light modulators (UP-SLMs) are proposed and demonstrated by simulation and experiment. UP-SLMs, which consist of unitarily coupled electrically controllable wave plates, convert the optically anisotropic properties of the paired two wave plates into an effective single isotropic phase plate and can be realized with ...
Minho, Choi, Jaewu, Choi
openaire   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source