Results 81 to 90 of about 365,427 (304)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The mode of action of spatial repellents and their impact on vectorial capacity of Anopheles gambiae sensu stricto. [PDF]

, 2014
Malaria vector control relies on toxicity of insecticides used in long lasting insecticide treated nets and indoor residual spraying. This is despite evidence that sub-lethal insecticides reduce human-vector contact and malaria transmission.
Ngonyani, Hassan, Simfukwe, Emmanuel T., Moore, Sarah J, Moore, Sarah J., Maia, Marta F., Mseka, Antony, Lorenz, Lena M., Moore, Jason, Ogoma, Sheila B., Simfukwe, Emmanuel T, Sheila B Ogoma, Hassan Ngonyani, Lena M Lorenz, Jason Moore, Maia, Marta F, Sarah J Moore, Ogoma, Sheila B, Lorenz, Lena M, Marta F Maia, Antony Mseka, Emmanuel T Simfukwe   +20 more
core   +1 more source

Quantum fluctuations spatial mode profiler

, 2023
The spatial mode is an essential component of an electromagnetic field description, yet it is challenging to characterize it for optical fields with the low average photon number, such as in a squeezed vacuum.
Savannah L. Cuozzo, Hwang Lee, Lior Cohen, Eugeniy E. Mikhailov, Novikova, Irina, Irina Novikova, Charris Gabaldon, Barge, Pratik, Lee, Hwang, Gabaldon, Charris, Cohen, Lior, Pratik Barge, Mikhailov, Eugeniy E., Cuozzo, Savannah L.   +13 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Short-distance commuting mode selection mechanism considering spatial heterogeneity

Shenzhen Daxue xuebao. Ligong ban
Short-distance traveling is a vital component of students' daily commuting routines. Guiding the mode choices of short-distance school commuters is crucial for fostering healthy student development and alleviating road traffic congestion during peak ...
LIU Yang, FU Tingyou, SHI Zhuangbin, HE Mingwei   +3 more
doaj   +1 more source

Titanium-Based Microbolometers: Control of Spatial Profile of Terahertz Emission in Weak Power Sources

Applied Sciences, 2020
Terahertz (THz) imaging and spectroscopy set-ups require fine optical alignment or precise control of spatial mode profile. We demonstrate universal, convenient and easy-to-use imaging—resonant and broadband antenna coupled ultrasensitive titanium-based ...
Linas Minkevičius, Liang Qi, Agnieszka Siemion, Domas Jokubauskis, Aleksander Sešek, Andrej Švigelj, Janez Trontelj, Dalius Seliuta, Irmantas Kašalynas, Gintaras Valušis   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Highly accurate spatial mode generation using spatial cross modulation method for mode division multiplexing [PDF]

, 2016
We propose a spatial mode generation technology using spatial cross modulation (SCM) for mode division multiplexing (MDM). The most well-known method for generating arbitrary complex amplitude fields is to display an off-axis computer-generated hologram (
Akihisa Tomita, Sakuma, Hiroki, Shibukawa, Atsushi, Atsushi Shibukawa, Tomita, Akihisa, Goto, Yuta, Atsushi Okamoto, Yuta Goto, Okamoto, Atsushi, Hiroki Sakuma   +9 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source