Results 101 to 110 of about 365,427 (304)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Single-mode fiber length for wavefront filtering
, 2008 Stellar nulling interferometry offers the possibility of direct imaging of extrasolar planets necessary for the detection of extra-terrestrial life. Achieving optimum performance from the interferometers requires that the wavefronts of light reaching the
Dasgupta, Sonali +2 more
core
Multiresonant plasmonics with spatial mode overlap: overview and outlook
Nanophotonics, 2019 Plasmonic nanostructures can concentrate light and enhance light-matter interactions in the subwavelength domain, which is useful for photodetection, light emission, optical biosensing, and spectroscopy.
Safiabadi Tali Seied Ali, Zhou Wei
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Integrated phononic crystal resonators based on adiabatically-terminated phononic crystal waveguides
AIP Advances, 2016 In this letter, we demonstrate a new design for integrated phononic crystal (PnC) resonators based on confining acoustic waves in a heterogeneous waveguide-based PnC structure.
Razi Dehghannasiri +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Cycle commuting in Belgium: Spatial determinants and ‘re-cycling’ strategies [PDF]
This paper attempts to explain the spatial variation of the use of a bicycle for commuting to work at the level of the 589 municipalities in Belgium. Regression techniques were used and special attention was paid to autocorrelation, heterogeneity and ...
VANDENBULCKE, Grégory +3 more
core
Geospatial HealthEquitable spatial accessibility to vaccination sites is essential for enhancing the effectiveness of infectious disease prevention and control. While traffic modes significantly influence the evaluation of spatial accessibility to vaccination sites ...
Wentao Yang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source