Results 81 to 90 of about 364,113 (314)

Spatial organization to facilitate action

PLOS ONE, 2019
Humans exert a great deal of control over our local environments-selecting and arranging the many objects around us on the basis of conflicting task-demands, aesthetic preferences, and habitual convenience. Because routine behaviour necessitates that we regularly find and access these objects, the particular arrangements we choose can influence the ...
Grayden J. F. Solman, Alan Kingstone
openaire   +3 more sources

Different Faces of Participation: Social Involvement in Rural Planning in Poland

Quaestiones Geographicae
The article deals with public participation in two dimensions of local rural planning: development and spatial planning. The research consisted in determining, with the help of constructed indexes, the level of participation of rural residents in various
BEDNAREK-SZCZEPAŃSKA MARIA, MAZUREK DAMIAN   +1 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A framework for the analysis of the influence of rainfall spatial organization and basin morphology on flood response [PDF]

, 2013
This work describes the derivation of a set of statistics, termed spatial moments of catchment rainfall, that quantify the dependence between rainfall spatial organization, basin morphology and runoff response.
Zoccatelli, Davide
core  

spatial-clusters code and data files

, 2023
Code and result files for "A spatial signal of niche differentiation in tropical forests".Please read the readme file to understand the organization of the code and data files.
Rafael D'Andrea (17295504), Mihir Umarani (17294476), John Wang (17295515), James O'Dwyer (17295507)   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Temporal and spatial variability of ice cover occurrence on Carpathian rivers: a regional perspective [PDF]

Hydrology and Earth System Sciences
This article presents an analysis of the temporal and spatial variability of ice cover (IC) occurrence from 1950 to 2020 in the Polish part of the Carpathians, with a focus on climatic conditions and the impact of reservoir operations. Data on border ice
M. Fukś, Ł. Wiejaczka
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

More is not necessarily better: The role of cover and spatial organization of resource sinks in the restoration of patchy drylands [PDF]

, 2020
A low-cost restoration action in patchy drylands worldwide is the installation of obstructions (hereafter, resource sinks) to break runoff pathways and retain resources.
Baudena, M., Garcia Mayor, A., Berghuis, Paul, Rietkerk, M.G.   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source