Results 121 to 130 of about 160,073 (300)

Convergence in Mississippi: A Spatial Approach. [PDF]

Mississippi constitutes an interesting case study for analyzing the income convergence process because of several characteristics, such as the fairly large number of counties, its relative homogeneous economy and its low percapita income compared with ...
Mihai Nica
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Evolution of Hierarchical Structure and Spatial Pattern of Coastal Cities in China – Based on the Data of Distribution of Marine-Related Enterprises

Polish Maritime Research, 2017
In this paper, a comprehensive research of the evolution of the hierarchical structure and spatial pattern of coastal cities in China was conducted based on the data of distribution of the headquarters and subsidiaries of marine-related enterprises in ...
Wang Lili, Xiao Wenwen, Wang Chengwei
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

SPATIAL ANALYSIS OF EMPLOYMENT AND POPULATION DENSITY: THE CASE OF THE AGGLOMERATION OF DIJON, 1999 [PDF]

The aim of this paper is to analyze the intra-urban spatial distributions of population and employment in the agglomeration of Dijon (regional capital of Burgundy, France).
Julie Le Gallo, Catherine Baumont, Cem Ertur   +2 more
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Pattern formation in reaction diffusion models with spatially inhomogeneous diffusion coefficients

, 1992
Reaction-diffusion models for biological pattern formation have been studied extensively in a variety of embryonic and ecological contexts. However, despite experimental evidence pointing to the existence of spatial inhomogeneities in various biological ...
Sherratt, J. A., BENSON, D, MAINI, P, Maini, P. K., Benson, D. L., SHERRATT, J, Sherratt, Jonathan Adam, Benson, D.L., Maini, P.K., MAINI, Philip   +9 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Assessing green production efficiency and spatial characteristics of China’s real estate industry based on the undesirable super-SBM model

Scientific Reports
As China strives to balance rapid urbanization with environmental conservation, increasing attention is being paid to the pursuit of green production efficiency (GPE) in the real estate industry.
Bo-Wen An, Pei-Yuan Xu, Chun-Yu Li, Lan-Yue Zhang, Qiu-Ping Guo   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The evolution of the spatial and sectoral patterns in Ile-de-France over 1978-1997 [PDF]

The aim of this paper is to analyze the intra-urban spatial distribution of employment in the agglomeration of Ile-de-France in 1978 and 1997. In that purpose, exploratory spatial data analysis is used in order to identify employment centers and a ...
Julie Le Gallo, Rachel Guillain, Céline Boiteux-Orain   +2 more
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