Results 131 to 140 of about 160,073 (300)

Evolution characteristics and pattern optimization of land use conflict in inland river Basin from the perspective of production-living-ecological.

open access: yesPLoS ONE
Identification of the process and intrinsic mechanisms of land use conflicts is a prerequisite for adjusting optimal national spatial planning strategies.
Wanzhuang Huang   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Characteristics and Influencing Factors of Spatial Agglomeration Evolution in China’s Logistics Industry: An Analysis Based on City-Level Panel Data

open access: yesSystems
The past few years has witnessed the rapid development of China’s logistics industry. However, the industry still faces problems such as uneven regional development, low-cost efficiency, insufficient technology application, and pressure for green ...
Ningning Huang, Jinzhuo Wu
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Strategies of human spatial cognition: cognitive and behavioural trade-offs

open access: yes, 2009
Human spatial strategies are heuristics that allocate cognitive and behavioural resources for navigation tasks. These spatial strategies help the individual optimize its interactions with the surrounding space through functional trade-offs between the ...
Makány, Tamás
core  

The Europeanisation of Spatial Planning in Britain: New Spatial Ideas for Old Territories? [PDF]

open access: yes, 2004
[Introduction]. This paper explores the representation of European space in images, and the significance of these images in building and reproducing policy discourses of European space.
Richardson, Tim   +2 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Artificial Ontogenies: A Computational Model of the Control and Evolution of Development

open access: yes, 2006
Understanding the behaviour of biological systems is a challenging task. Gene regulation, development and evolution are each a product of nonlinear interactions between many individual agents: genes, cells or organisms.
Geard, Nicholas Lewis, Geard, N L
core  

Temporal and spatial evolution of global major grain trade patterns

open access: yesJournal of Integrative Agriculture
The complex and volatile international landscape has significantly impacted global grain supply security. This study uses a complex network analysis model to examine the evolution and trends of the global major grain trade from 1990 to 2020, focusing on network topology, centrality ranking, and community structure. There are three major findings. First,
Ziqi Yin   +5 more
openaire   +2 more sources

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