Results 101 to 110 of about 3,267,627 (304)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Superensemble forecast of respiratory syncytial virus outbreaks at national, regional, and state levels in the United States

open access: yesEpidemics, 2019
Respiratory syncytial virus (RSV) infections peak during the winter months in the United States, yet the timing, intensity, and onset of these outbreaks vary each year.
Julia Reis   +3 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Fiscal Year 2006

open access: yes, 2006
Annual report of the Texas Skill Standards Board describing goals, activities, and accomplishments during fiscal year ...
Texas Skill Standards Board
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Fiscal Year 2010

open access: yes, 2010
Annual report of the Texas Skill Standards Board describing goals, activities, and accomplishments during fiscal year ...
Texas Skill Standards Board
core  

Using climate regionalization to understand Climate Forecast System Version 2 (CFSv2) precipitation performance for the Conterminous United States (CONUS)

open access: yesGeophysical Research Letters, 2016
Dynamically based seasonal forecasts are prone to systematic spatial biases due to imperfections in the underlying global climate model (GCM). This can result in low‐forecast skill when the GCM misplaces teleconnections or fails to resolve geographic ...
Satish K. Regonda   +3 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Spatial factors and the employment of blacks at the firm level [PDF]

open access: yes
In this paper we use data from a new survey of over 3,000 employers in four major metropolitan areas to investigate the determinants of black employment and wages at the firm level.
K. R. Ihlanfeldt, H. J. Holzer
core  

Diagnosing and Conditionally Correcting X-Band Radar Underestimation in Cyprus: A Cross-Validated Evaluation of Spatial Merging and Machine Learning Approaches

open access: yesRemote Sensing
Radar-based Quantitative Precipitation Estimation (QPE) in semi-arid Mediterranean climates is critically challenged by systematic underestimation of shallow precipitation, yet gauge–radar merging frameworks tailored to such environments remain poorly ...
Harshad S. Hanmante   +3 more
doaj   +1 more source

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