Results 131 to 140 of about 47,554 (301)

Wayfinding Strategy and Gender – Testing the Mediating Effects of Wayfinding Experience, Personality and Emotions

open access: yesPsychology Research and Behavior Management, 2020
Magdalena Mendez-Lopez,1 Camino Fidalgo,1 Jorge Osma,1 M-Carmen Juan2 1Departamento de Psicología y Sociología, Universidad de Zaragoza, IIS Aragón, Facultad de Ciencias Sociales y Humanas, Teruel, Spain; 2Instituto Universitario de ...
Mendez-Lopez M   +3 more
doaj  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Assessing the spatial and temporal variation in the skill of precipitation forecasts from an NWP model

open access: yes, 2008
It is becoming increasingly important to be able to verify the spatial accuracy of precipitation forecasts, especially with the advent of high-resolution numerical weather prediction (NWP) models. In this article, the fractions skill score (FSS) approach
Roberts, Nigel, Nigel Roberts
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Spatial Skills Activities in the Middle School Mathematics Teachers' Toolkit: The Impact of Spatial Skill Activities on Mathematical Thinking

open access: yes, 2018
This study investigated the impact of the incorporation of spatial skill activities into their pedagogical repertoire by middle school mathematics teachers on the mathematical reasoning of their students. Current research suggests that success in spatial
Younger, Martha
core   +1 more source

Skill-Biased Share-Altering Technical Change in Spatial General Equilibrium [PDF]

open access: yes, 2011
The paper consider the skill-biased "share-altering" technical change hypothesis in a spatial general equilibrium model where skilled and unskilled individual may exhibit different preferences for local amenities.
de Blasio, Guido   +2 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Evaluation of environmental design students’ sectioning skill with the Turkish version of the Santa Barbara Solids Test

open access: yesIDA: International Design and Art Journal
Given the significance of sectioning skill in higher education and its malleability through training, it is imperative to measure this spatial skill and track its development by using an appropriate instrument. The Santa Barbara Solids Test is a spatial
Kenan Eren Şansal   +2 more
doaj   +2 more sources

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