Results 131 to 140 of about 3,267,627 (304)

Evaluation of environmental design students’ sectioning skill with the Turkish version of the Santa Barbara Solids Test

open access: yesIDA: International Design and Art Journal
Given the significance of sectioning skill in higher education and its malleability through training, it is imperative to measure this spatial skill and track its development by using an appropriate instrument. The Santa Barbara Solids Test is a spatial
Kenan Eren Şansal   +2 more
doaj   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Spatial Mismatch and Skill Accumulation

open access: yes
Increasing returns in matching between skilled workers and firms create a local thick-market externality when labour markets are geographically segmented. This generates an agglomeration force that can offset the dispersion force due to local competition
Ottaviano, Gianmarco Ireo Paolo   +1 more
core  

Adjusting to Skill Shortages: Complexity and Consequences [PDF]

open access: yes
Skill shortages are often portrayed as a major problem for the economies of many countries including the Australian economy. Yet, there is surprisingly little evidence about their prevalence, causes and consequences.
Healy, Joshua   +2 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Spatial Variability in Seasonal Prediction Skill of SSTs: Inherent Predictability or Forecast Errors?

open access: yes, 2018
Seasonal prediction skill of SSTs from coupled models has considerable spatial variations. In the tropics, SST prediction skill in the tropical Pacific clearly exceeds prediction skill over the Atlantic and Indian Oceans.
Jieshun Zhu, Arun Kumar
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Skill-based learning

open access: yes, 2009
Skill-based ...
Jane Maidment (13050504)
core  

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