Results 161 to 170 of about 47,554 (301)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Daytime sleep following observational practice does not enhance a visual-spatial and a motor representation. [PDF]

Exp Brain Res
Panzer S, Hofstetter N, Schreiber M, Wright DL.   +3 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Not All Math Activities Are Equal in Terms of Gender Stereotypes. [PDF]

Sex Roles
Merrick M, White AD, Diekman AB, Fyfe ER.   +3 more
europepmc   +1 more source

The role of expertise, semantics, and learning in spatial memory

, 2012
This research investigates the mechanisms that underpin object location memory. It approaches this endeavour by examining a recently reported phenomenon of spatial memory, that of exclusivity.
Dunn, TJ
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A Formal Investigation of Human Spatial Control Skills: Mathematical Formalization, Skill Development, and Skill Assessment

, 2016
University of Minnesota Ph.D. dissertation. July 2016. Major: Aerospace Engineering and Mechanics. Advisor: Berenice Mettler. 1 computer file (PDF); x, 130 pages.Spatial control behaviors account for a large proportion of human everyday activities from
Li, Bin
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Assessing the utility of statistical downscaling for subseasonal temperature forecasts. [PDF]

Sci Rep
Duzenli E, Ramon J, Torralba V, Pickard S, Muñoz ÁG, Bojovic D.   +5 more
europepmc   +1 more source

Spatial patterns of adoption of just-in-time manufacturing [PDF]

We study the spatial pattern of Just-in-Time (JIT) adoption for a sample of medium-sized and large Spanish manufacturing firms. JIT differs from other advanced manufacturing technologies because it relates directly to the spatial coordination of a firms’
Ruth Rama, Rafael Pardo, Adelheid Holl
core