Results 41 to 50 of about 323,364 (251)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
MEAN VALUES FOR HOMOGENEOUS STIT TESSELLATIONS IN 3D
Recently (Nagel and Weiss, 2005), the class of homogeneous random tessellations that are stable under the operation of iteration (STIT) was introduced. In the present paper this model is reviewed and new results for the mean values of essential geometric
Werner Nagel, Viola Weiss
doaj +1 more source
Spatial Study of Enzymatic Activities from Bacterial Isolates in a Mediterranean Urban Park
Urban parks are a rich source of microbial diversity, as they are heavily used by city residents. In this study, we sampled a Mediterranean park and were able to isolate bacteria that have the ability to inhibit the growth of control microorganisms.
Sergi Maicas, Jaume Segura-Garcia
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Geographically weighted regression (GWR) is a spatial statistical technique that recognizes that traditional ‘global’ regression models may be limited when spatial processes vary with spatial context.
Taylor M. Oshan +4 more
doaj +1 more source
In this paper, we review overdispersed Bayesian generalized spatial conditional count data models. Their usefulness is illustrated with their application to infant mortality rates from Colombian regions and by comparing them with the widely used Besag ...
Mabel Morales-Otero +1 more
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Statistics Netherlands (CBS) has recently developed the whole population network (Person Network) file, based on administrative microdata, which includes over a billion interpersonal relationships among approximately 17 million inhabitants of the ...
Dino Pitoski, Hans Schmeets
doaj +1 more source
Forest degradation is an important issue in global environmental studies, albeit not yet well defined in quantitative terms. The present work addresses the problem, by starting with the assumption that forest spatial structure can provide an indication ...
Elsa C. De Grandi +3 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

