Results 191 to 200 of about 16,214,189 (289)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Tracing echoes from the past: a district-level analysis of thyroid cancer incidence and radiation exposure in post-Chornobyl Ukraine. [PDF]

BMJ Public Health
Levchuk N, Schöley J, Cilek L, Jasilionis D.   +3 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Making Spatial Experience Researchable in Architectural Studies: A Comparative Examination of Phenomenological Approaches

Betül Taş, Figen Gül Kafescioğlu
openalex   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A Spatiotemporal Causal Machine Learning Framework for Quantifying the Impact of PM_2.5 on Asthma at the Community Level. [PDF]

Geohealth
Li J, Wang X, Chu HW.
europepmc   +1 more source

Prognostic architecture of spatially resolved immune ecosystems in colorectal cancer: a multiplex immunohistochemistry and machine learning study

Yan Lai, Juan Wang, XiaoZhuang Yong, Zhen Wu, Guangxiu Guo, Yanzhen Sun, Gan Xie, Jinlin Zeng, Ning Liu, Qin Chen, Yaohong Wu, Fangjun Zeng, Cheng Yang   +12 more
openalex   +1 more source

Spatially Resolved Latent and Sensible Heat Fluxes of a Cold Air Outbreak Using Wavelet Analysis of Airborne Observations: A CAESAR Case Study [PDF]

Michael Flynn McGinnity, Zhien Wang, Guo Lin, Paquita Zuidema, Bart Geerts, John J. Cassano, Samuel Ephraim, Yufei Chu, Christopher Kruse   +8 more
openalex   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Biological sex and disease architecture in systemic sclerosis: a multilayer translational framework for precision medicine. [PDF]

Front Immunol
Tian Y, Tian Z.
europepmc   +1 more source