Results 191 to 200 of about 3,212,185 (292)

Naturalistic spatial education engages distinct neural processes for mental rotation, cognitive load, and linguistic demands. [PDF]

Proc Natl Acad Sci U S A
Gacetta EB, Laws ML, Aulet LS, Ozaydin TS, Tsay JS, Zapanta C, Cantlon JF.   +6 more
europepmc   +1 more source

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

CCCView: A Knowledge Platform for Integrated Analysis of Spatial Transcriptomic Cell-Cell Communication. [PDF]

Int J Mol Sci
Qi Z, Wu C, Qian Q, Zeng Z, Xiao J, Zhao D.   +5 more
europepmc   +1 more source

Parkinson Disease Subtype Stability and Eventual Convergence

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok, Christina N. Lessov‐Schlaggar, Abdulmunaim M. Eid, Erin R. Foster, Baijayanta Maiti, Hailee Domash, Helen Hwang, Richard J. Perrin, Paul T. Kotzbauer, Joel S. Perlmutter, Meghan C. Campbell   +10 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Visualizing the future: impact of holographic visualization on teaching minimally invasive veneer preparation: a randomized controlled trial. [PDF]

BMC Med Educ
Janson M, Lederer ML, Dalhoff CM, Barbe AG, Liebermann A, Schoppmeier CM.   +5 more
europepmc   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

A Conceptual Framework for 4D Holographic Visualization in Gastrointestinal Endoscopy: Toward Externalized Spatiotemporal Cognition. [PDF]

JMIR XR Spat Comput
Yamaguchi H, Fukuzawa M, Kawai T, Yamanishi F, Muramatsu T, Ichimiya T, Kagawa Y, Uchida K, Madarame A, Morise T, Yamauchi Y, Kono S, Naito S, Itoi T.   +13 more
europepmc   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

Spatial transcriptomic analysis of neurons at the glioma infiltration front: A case study. [PDF]

Brain Pathol
Satomi K, Takami H, Onizuka H, Saito K, Yoshioka T, Nagane M, Suzuki Y, Ichimura K, Shibahara J.   +8 more
europepmc   +1 more source