Results 31 to 40 of about 366,164 (211)

Measuring the impact of student success retention initiatives for engineering students at a private research university

open access: yesFrontiers in Education, 2022
IntroductionStudent success in Science, Technology, Engineering, and Mathematics (STEM) is a national concern. To increase engineering retention and graduation rates at a small private institution, a university council developed a binary classifier to ...
David P. Wick   +10 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

FEATURES OF THE MODEL OF A SPECIALIZED GEOSPATIAL DATABASE FOR VISUALIZING INDICATORS OF HUMAN SOCIO-ECONOMIC SECURITY IN WARTIME CONDITIONS [PDF]

open access: yesAcademy Review
The socio-economic security of the state is not only a guarantee of its citizens’ safety but also a guarantee of a decent standard of living. Studying the impact of military conflicts on human social security reveals weaknesses in the implementation of
Zakharii S. Varnalii   +3 more
doaj   +1 more source

Application of GeoGebra in the Teaching of Descriptive Geometry: Sections of Solids

open access: yesMathematics, 2022
Technologies came to revolutionize the teaching of technical design; they brought resources that enabled 3D and 2D graphic simulation. The objective of this research is to understand how the implementation of the dynamic software GeoGebra on the topic of
Cacilda H. Chivai   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Calculations and Expectations: How Engineering Students Describe Three-dimensional Forces

open access: yesCanadian Journal for the Scholarship of Teaching and Learning, 2013
The premise of student-centered teaching is to respond to the ways in which students engage with the contextand content of their learning, and therefore the purpose of this study was to find out how students visualizethree-dimensional statics problems ...
Janice E. Miller-Young
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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